About: Characteristics of a coronavirus causing vomition and wasting in pigs

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About: Characteristics of a coronavirus causing vomition and wasting in pigs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characteristics of a coronavirus causing vomition and wasting in pigs
Creator	Callebaut, P
Source	Medline; PMC
abstract	Some characteristics of a virus, isolated from the tonsils of 2 pigs with clinical signs of inappetence and vomition and designated VW572 were examined. It induced the formation of syncytia in primary pig kidney cell cultures, caused hemadsorption and hemagglutination using chicken, turkey, rat and mouse erythrocytes. In growth curve experiments, infectious virus was produced intracellularly starting at 6 hours after inoculation and was followed by rapid release of the virus from the infected cells. The virus contains ribonucleic acid, is ether sensitive and has a size between 100 and 220 nm. At 37° C, the infectivity titer decreased about 2 log(10)TCID(50) per 24 hours. The viral population was heterogeneous as indicated by the rate of inactivation by U.V. irradiation and acid pH. Some hemagglutinating activity was left after complete loss of infectivity by ether-, temperature- and U.V. treatment. The VW 572 isolate is antigenically related if not identical to isolates from Canada, U.S.A. and England which were classified as a porcine coronavirus. Oronasal and intracerebral inoculation of the VW572 isolate in colostrum deprived pigs resulted in clinical disease after an incubation period of 6 and 4 days, respectively. Signs were characterized by depression, vomition, loss of appetence with rapid weakness in young pigs and vomition with progressive wasting in older pigs. Virus was isolated from nasal and pharyngeal swabs, nasal mucosa, tonsils, lungs and hind brains but not from rectal swabs or other organs tested. Virus could not be isolated later than 8 days after inoculation. Hemagglutination inhibiting and neutralizing antibodies were detected in sera at 6 days and 9 days after inoculation, respectively.
has issue date	1974-01-01(xsd:dateTime)
bibo:doi	10.1007/bf01242179
bibo:pmid	4823866
has license	no-cc
sha1sum (hex)	d8ae456e7e9cf81b3d1efc17d3d559d4d1c30e11
schema:url	https://doi.org/10.1007/bf01242179
resource representing a document's title	Characteristics of a coronavirus causing vomition and wasting in pigs
has PubMed Central identifier	PMC7087132
has PubMed identifier	4823866
schema:publication	Arch Gesamte Virusforsch
resource representing a document's body	covid:d8ae456e7e9cf81b3d1efc17d3d559d4d1c30e11#body_text
is schema:about of	named entity 'U.S.A.' named entity 'CHARACTERISTICS' named entity 'TEMPERATURE' named entity 'TREATMENT' named entity 'IRRADIATION' named entity 'RAT' named entity 'PRIMARY' named entity 'RELEASE' named entity 'ENGLAND' named entity 'ETHER' named entity 'COMPLETE' named entity 'HETEROGENEOUS' named entity 'CHICKEN' named entity 'U.V.' named entity 'VIRUS' covid:arg/d8ae456e7e9cf81b3d1efc17d3d559d4d1c30e11 named entity 'EXPERIMENTS' named entity 'PER 24 HOURS' named entity 'CAUSED' named entity 'RELATED' named entity 'INFECTIOUS' named entity 'USING' named entity 'STARTING' named entity 'TITER' named entity '6 HOURS' named entity 'TONSILS' named entity 'HEMAGGLUTINATION' named entity 'TURKEY' named entity 'RATE' named entity 'DESIGNATED' named entity 'ACID' named entity 'VIRAL' named entity 'CLASSIFIED' named entity 'INFECTIVITY' named entity 'RIBONUCLEIC ACID' named entity '100' named entity 'FOLLOWED BY' named entity 'EXAMINED' named entity 'FORMATION' named entity 'CORONAVIRUS' named entity 'PIG' named entity 'CELL CULTURES' named entity 'MOUSE' named entity 'ISOLATED' named entity '220' named entity 'ABOUT' named entity 'ACTIVITY' named entity 'CANADA' named entity 'ERYTHROCYTES' named entity 'INFECTED' named entity 'RAPID' named entity 'SENSITIVE' named entity 'PIGS' named entity 'HEMADSORPTION' named entity 'SIZE' named entity 'GROWTH CURVE' named entity 'CONTAINS' named entity 'INDUCED' named entity 'CELLS' named entity 'INDICATED' named entity 'ISOLATE' named entity 'POPULATION' named entity 'IDENTICAL' named entity 'KIDNEY CELL' named entity 'PORCINE' named entity 'INACTIVATION' named entity 'LOSS OF' named entity 'INOCULATION' named entity 'DECREASED' named entity 'LEFT' named entity 'ribonucleic acid' named entity 'cell cultures' named entity 'virus' named entity 'infectivity' named entity 'hemagglutination' named entity 'titer' named entity 'pig' named entity 'virus' named entity 'gastrointestinal tract' named entity 'nasal mucosa' named entity 'titration'

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