About: Animal lectins: potential receptors for ginseng polysaccharides

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About: Animal lectins: potential receptors for ginseng polysaccharides Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Animal lectins: potential receptors for ginseng polysaccharides
Creator	Kang, Young-Sun Park, Jin-Yeon Nah, Seung-Yeol Cho, Eun Loh, So
Source	PMC
abstract	Panax ginseng Meyer, belonging to the genus Panax of the family Araliaceae, is known for its human immune system-related effects, such as immune-boosting effects. Ginseng polysaccharides (GPs) are the responsible ingredient of ginseng in immunomodulation, and are classified as acidic and neutral GPs. Although GPs participate in various immune reactions including the stimulation of immune cells and production of cytokines, the precise function of GPs together with its potential receptor(s) and their signal transduction pathways have remained largely unknown. Animal lectins are carbohydrate-binding proteins that are highly specific for sugar moieties. Among many different biological functions in vivo, animal lectins especially play important roles in the immune system by recognizing carbohydrates that are found exclusively on pathogens or that are inaccessible on host cells. This review summarizes the immunological activities of GPs and the diverse roles of animal lectins in the immune system, suggesting the possibility of animal lectins as the potential receptor candidates of GPs and giving insights into the development of GPs as therapeutic biomaterials for many immunological diseases.
has issue date	2015-12-17(xsd:dateTime)
bibo:doi	10.1016/j.jgr.2015.12.006
bibo:pmid	28123316
has license	cc-by-nc-nd
sha1sum (hex)	d87ca5cebffb0dcd7717487a8d2ed9861b237f46
schema:url	https://doi.org/10.1016/j.jgr.2015.12.006
resource representing a document's title	Animal lectins: potential receptors for ginseng polysaccharides
has PubMed Central identifier	PMC5223067
has PubMed identifier	28123316
schema:publication	J Ginseng Res
resource representing a document's body	covid:d87ca5cebffb0dcd7717487a8d2ed9861b237f46#body_text
is schema:about of	named entity 'RECEPTORS' named entity 'ARALIACEAE' named entity 'CARBOHYDRATE' named entity 'PATHOGENS' named entity 'GIVING' named entity 'IMPORTANT' named entity 'IMMUNOMODULATION' named entity 'RESPONSIBLE' named entity 'KNOWN' named entity 'GENUS' named entity 'PRODUCTION' named entity 'EFFECTS' named entity 'BELONGING' named entity 'GPS' named entity 'STIMULATION' named entity 'IMMUNOLOGICAL' named entity 'IMMUNOLOGICAL DISEASES' named entity '28S' named entity 'vivo' named entity 'biological functions' named entity 'insights' named entity 'POTENTIAL' named entity 'ORG' named entity 'POLYSACCHARIDES' named entity 'ANIMAL LECTINS' named entity 'POSSIBILITY OF' named entity 'PLAY' named entity 'PANAX' named entity 'RECEPTOR' named entity 'ROLES' named entity 'INGREDIENT' named entity 'DIVERSE' named entity 'SUGAR' named entity 'HOST CELLS' named entity 'MEYER' named entity 'CYTOKINES' named entity 'CARBOHYDRATES' named entity 'SPECIFIC' named entity 'NC-' named entity 'LICENSE' named entity 'VARIOUS' named entity 'POTENTIAL' named entity 'REACTIONS' named entity 'RELATED' named entity 'LARGELY' named entity 'HAVE' named entity 'BOOSTING' named entity 'BIOMATERIALS' named entity 'DIFFERENT' named entity 'ACTIVITIES' named entity 'IMMUNE' named entity 'FOUND' named entity 'UNKNOWN' named entity 'BINDING PROTEINS' named entity 'THEIR' named entity 'DEVELOPMENT' named entity 'POLYSACCHARIDES' named entity 'FAMILY' named entity 'PRECISE' named entity 'NEUTRAL' named entity 'GINSENG' named entity 'IMMUNE CELLS' named entity 'ITS' named entity 'REVIEW' named entity 'HIGHLY' named entity 'ANIMAL LECTINS' named entity 'HUMAN' named entity 'FUNCTION' named entity 'CLASSIFIED' named entity 'IN VIVO' named entity 'INSIGHTS' named entity 'INCLUDING' named entity 'IMMUNE SYSTEM' named entity 'BIOLOGICAL FUNCTIONS' named entity 'PANAX GINSENG' named entity 'ACIDIC' named entity 'THERAPEUTIC'

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