About: Viruses and bacteria in acute asthma exacerbations – A GA(2)LEN‐DARE systematic review

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About: Viruses and bacteria in acute asthma exacerbations – A GA(2)LEN‐DARE systematic review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viruses and bacteria in acute asthma exacerbations – A GA(2)LEN‐DARE systematic review
Creator	Bont, L Rohde, G Sl, Johnston Johnston, S Papadopoulos, N Almqvist, C Holgate, S Bossios, A Psarras, S Agache, I Bom, A Bom, Todo Bonini, S Bousquet, J Braido, F Bruno, A Brusselle, G Canonica, G Carlsen, K Chanez, P Christodoulou, I Eller, E Fokkens, W Garcia-Garcia, M Gjomarkaj, M Gw, Cano-Nica Haahtela, T Jb, Watelet Kh, Carlsen Konstantinou, G Kowalski, Konstantinou Kowalski, M Lewandowska-Polak, A Lewandowska-Polak, M Lødrup-Carlsen, K Malkusova, I Mullol, J Mä Kelä 15, M Ng, Papadopoulos Nieto, A Ozdemir, C Panzner, P Popov, T Roumpedaki, E Rukhadze, M St, Holgate Stipic-Markovic, A Toskala, E Van Cauwenberge P, Van Drunen C, Toskala Van Cauwenberge, P Van Drunen, C Watelet, J Wj, Fokkens Xatzipsalti, M Xepapadaki, P Zuberbier, &
Source	Medline; PMC
abstract	To cite this article: Papadopoulos NG, Christodoulou I, Rohde G, Agache I, Almqvist C, Bruno A, Bonini S, Bont L, Bossios A, Bousquet J, Braido F, Brusselle G, Canonica GW, Carlsen KH, Chanez P, Fokkens WJ, Garcia‐Garcia M, Gjomarkaj M, Haahtela T, Holgate ST, Johnston SL, Konstantinou G, Kowalski M, Lewandowska‐Polak A, Lødrup‐Carlsen K, Mäkelä M, Malkusova I, Mullol J, Nieto A, Eller E, Ozdemir C, Panzner P, Popov T, Psarras S, Roumpedaki E, Rukhadze M, Stipic‐Markovic A, Todo Bom A, Toskala E, van Cauwenberge P, van Drunen C, Watelet JB, Xatzipsalti M, Xepapadaki P, Zuberbier T. Viruses and bacteria in acute asthma exacerbations – A GA(2)LEN‐DARE systematic review. Allergy 2011; 66: 458–468. ABSTRACT: A major part of the burden of asthma is caused by acute exacerbations. Exacerbations have been strongly and consistently associated with respiratory infections. Respiratory viruses and bacteria are therefore possible treatment targets. To have a reasonable estimate of the burden of disease induced by such infectious agents on asthmatic patients, it is necessary to understand their nature and be able to identify them in clinical samples by employing accurate and sensitive methodologies. This systematic review summarizes current knowledge and developments in infection epidemiology of acute asthma in children and adults, describing the known impact for each individual agent and highlighting knowledge gaps. Among infectious agents, human rhinoviruses are the most prevalent in regard to asthma exacerbations. The newly identified type‐C rhinoviruses may prove to be particularly relevant. Respiratory syncytial virus and metapneumovirus are important in infants, while influenza viruses seem to induce severe exacerbations mostly in adults. Other agents are relatively less or not clearly associated. Mycoplasma and Chlamydophila pneumoniae seem to be involved more with asthma persistence rather than with disease exacerbations. Recent data suggest that common bacteria may also be involved, but this should be confirmed. Although current information is considerable, improvements in detection methodologies, as well as the wide variation in respect to location, time and populations, underline the need for additional studies that should also take into account interacting factors.
has issue date	2010-11-18(xsd:dateTime)
bibo:doi	10.1111/j.1398-9995.2010.02505.x
bibo:pmid	21087215
has license	no-cc
sha1sum (hex)	d4988b8ba76de95395bcaefe0e73f4c5b79bd437
schema:url	https://doi.org/10.1111/j.1398-9995.2010.02505.x
resource representing a document's title	Viruses and bacteria in acute asthma exacerbations – A GA(2)LEN‐DARE systematic review
has PubMed Central identifier	PMC7159474
has PubMed identifier	21087215
schema:publication	Allergy
resource representing a document's body	covid:d4988b8ba76de95395bcaefe0e73f4c5b79bd437#body_text
is schema:about of	named entity 'asthmatic' named entity 'asthma' named entity 'A major' named entity 'individual' named entity 'wide' named entity 'acute' named entity 'BURDEN OF DISEASE' named entity 'METAPNEUMOVIRUS' named entity 'BUT' named entity 'ADULTS' named entity 'MYCOPLASMA' named entity 'TO IDENTIFY' named entity 'NECESSARY' named entity 'PATIENTS' named entity 'SEVERE' named entity 'SYSTEMATIC REVIEW' named entity 'ACUTE ASTHMA' named entity 'HUMAN' named entity 'PREVALENT' named entity 'CAUSED BY' named entity 'IMPORTANT' covid:arg/d4988b8ba76de95395bcaefe0e73f4c5b79bd437 named entity 'exacerbations' named entity 'regard' named entity 'persistence' named entity 'sensitive'

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