About: Characteristics and outcomes of COVID‐19 in hospitalized patients with and without diabetes

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Characteristics and outcomes of COVID‐19 in hospitalized patients with and without diabetes
Creator	Brochot, Etienne Desailloud, Rachel Maizel, Julien Dupont, Hervé Al-Salameh, Abdallah Andrejak, Claire Bennis, Youssef Ganry, Olivier Lalau, Jean-Daniel Lanoix, Jean-Philippe Schmit, Jean-Luc Deschasse, Guillaume Goeb, Vincent Jaureguy, Maité Lion, Sylvie Moyet, Julien Vaysse, Benoit
source	Medline; PMC
abstract	AIMS: Coronavirus disease 2019 (COVID‐19) is a rapidly progressing pandemic, with four million confirmed cases and 280,000 deaths at the time of writing. Some studies have suggested that diabetes is associated with a greater risk of developing severe forms of COVID‐19. The primary objective of the present study was to compare the clinical features and outcomes in hospitalized COVID‐19 patients with vs. without diabetes. METHODS: All consecutive adult patients admitted to Amiens University Hospital (Amiens, France) with confirmed COVID‐19 up until April 21(st), 2020, were included. The composite primary endpoint comprised admission to the intensive care unit (ICU) and death. Both components were also analyzed separately in a logistic regression analysis and a Cox proportional hazards model. RESULTS: A total of 433 patients (median age: 72; 238 (55%) men; diabetes: 115 (26.6%)) were included. Most of the deaths occurred in non‐ICU units and among older adults. Multivariate analyses showed that diabetes was associated neither with the primary endpoint (odds ratio (OR): 1.12; 95% confidence interval (CI): 0.66‐1.90) nor with mortality (hazard ratio: 0.73; 95%CI: 0.40‐1.34) but was associated with ICU admission (OR: 2.06; 95%CI 1.09‐3.92, p=0.027) and a longer length of hospital stay. Age was negatively associated with ICU admission and positively associated with death. DISCUSSION: Diabetes was prevalent in a quarter of the patients hospitalized with COVID‐19; it was associated with a greater risk of ICU admission but not with a significant elevation in mortality. Further investigation of the relationship between COVID‐19 severity and diabetes is warranted. This article is protected by copyright. All rights reserved.
has issue date	2020-07-19(xsd:dateTime)
bibo:doi	10.1002/dmrr.3388
bibo:pmid	32683744
has license	no-cc
sha1sum (hex)	d2599df20c1fcf8058807c56c37609dae435f8e6
schema:url	https://doi.org/10.1002/dmrr.3388
resource representing a document's title	Characteristics and outcomes of COVID‐19 in hospitalized patients with and without diabetes
has PubMed Central identifier	PMC7404605
has PubMed identifier	32683744
schema:publication	Diabetes Metab Res Rev
resource representing a document's body	covid:d2599df20c1fcf8058807c56c37609dae435f8e6#body_text
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