About: The interplay between immunosenescence and age-related diseases

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The interplay between immunosenescence and age-related diseases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The interplay between immunosenescence and age-related diseases
Creator	Barbé-Tuana, Florencia Bauer, Moisés Funchal, Giselle Maurmann, Rafael Raquel, Carine Schmitz, Richter
Source	Medline; PMC
abstract	The aging immune system (immunosenescence) has been implicated with increased morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation (inflammaging) are implicated with several age-related conditions. The expansion of late-differentiated T cells (CD28(−)), regulatory T cells, increased serum levels of autoantibodies, and pro-inflammatory cytokines were implicated with morbidities during aging. Features of accelerated immunosenescence can be identified in adults with chronic inflammatory conditions, such as rheumatoid arthritis, and are predictive of poor clinical outcomes. Therefore, there is an interplay between immunosenescence and age-related diseases. In this review, we discuss how the aging immune system may contribute to the development and clinical course of age-related diseases such as neurodegenerative diseases, rheumatoid arthritis, cancer, cardiovascular, and metabolic diseases.
has issue date	2020-08-03(xsd:dateTime)
bibo:doi	10.1007/s00281-020-00806-z
bibo:pmid	32747977
has license	no-cc
sha1sum (hex)	d225af23133f8d9de68dc68ef56cb89908ea271e
schema:url	https://doi.org/10.1007/s00281-020-00806-z
resource representing a document's title	The interplay between immunosenescence and age-related diseases
has PubMed Central identifier	PMC7398288
has PubMed identifier	32747977
schema:publication	Semin Immunopathol
resource representing a document's body	covid:d225af23133f8d9de68dc68ef56cb89908ea271e#body_text
is schema:about of	named entity 'development' named entity 'age-related diseases' named entity 'cardiovascular' named entity 'T cell' covid:arg/d225af23133f8d9de68dc68ef56cb89908ea271e named entity 'The' named entity 'cancer' named entity 'immunosenescence' named entity 'T cells' named entity 'regulatory T cells' named entity 'neurodegenerative diseases' named entity 'autoantibodies' named entity 'rheumatoid arthritis' named entity 'inflammaging' named entity 'clinical outcomes' named entity 'age-related diseases' named entity 'age-related diseases' named entity 'conditions' named entity 'insulin resistance' named entity 'T2D' named entity 'leptin' named entity 'endothelial cells' named entity 'IgG' named entity 'cytokines' named entity 'atherosclerotic plaques' named entity 'senescence' named entity 'collagen' named entity 'T2D' named entity 'cognitive impairment' named entity 'immunosenescence' named entity 'cognitively impaired' named entity 'metabolic dysfunction' named entity 'tissue regeneration' named entity 'therapeutic approaches' named entity 'cell receptor' named entity 'mice' named entity 'telomere shortening' named entity 'immunoediting' named entity 'autoantibodies' named entity 'metabolic dysfunction' named entity 'inflammatory responses' named entity 'CD28' named entity 'CD27' named entity 'tumor' named entity 'inflammatory mediators' named entity 'CD8 +' named entity 'hypertension' named entity 'organ failure' named entity 'Adverse effects' named entity 'TNFα' named entity 'senescent' named entity 'proinflammatory cytokines' named entity 'etiological' named entity 'IL-10' named entity 'CD28' named entity 'cohort study' named entity 'elderly individuals' named entity 'leukocyte' named entity 'CD28' named entity 'Hyperglycemia' named entity 'senescence' named entity 'Tregs' named entity 'executive functions' named entity 'Experimental models' named entity 'hyperglycemia' named entity 'cancer immunosurveillance' named entity 'Th2' named entity 'endoplasmic reticulum stress' named entity 'older people' named entity 'clinical outcomes' named entity 'secretion' named entity 'cell aging' named entity 'dementia' named entity 'cell adhesion molecules' named entity 'CD28' named entity 'healthy aging'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software