About: Chinese medicine for COVID-19: A protocol for systematic review and meta-analysis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Chinese medicine for COVID-19: A protocol for systematic review and meta-analysis
Creator	Chen, Qiu Xie, Chunguang Chen, Huizhen Xie, Ziyan Zhu, Yuxia
source	Medline; PMC
abstract	BACKGROUND: Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China. The clinical spectrum of SARS-CoV-2 infection appears to be wide, encompassing asymptomatic infection, mild upper respiratory tract illness, and severe viral pneumonia with respiratory failure and even death, with many patients being hospitalised with pneumonia. In China and East Asia, Chinese medicine has been widely used to treat diverse diseases for thousands of years. As an important means of treatment now, Chinese medicine plays a significant role in the treatment of respiratory diseases in China. The aim of this study is to assess the efficacy and safety of Chinese medicine for COVID-19. METHODS: We will search the following sources for the identification of trials: The Cochrane Library, PubMed, EMBASE, Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure Database (CNKI), Chinese Science and Technique Journals Database (VIP), and the Wanfang Database. All the above databases will be searched from the available date of inception until the latest issue. No language or publication restriction will be used. Randomized controlled trials will be included if they recruited participants with COVID-19 for assessing the effect of Chinese medicine vs control (placebo, no treatment, and other therapeutic agents). Primary outcomes will include chest CT and nucleic acid detection of respiratory samples. Two authors will independently scan the articles searched, extract the data from articles included, and assess the risk of bias by Cochrane tool of risk of bias. Disagreements will be resolved by consensus or the involvement of a third party. All analysis will be performed based on the Cochrane Handbook for Systematic Reviews of Interventions. Dichotomous variables will be reported as risk ratio or odds ratio with 95% confidence intervals (CIs) and continuous variables will be summarized as mean difference or standard mean difference with 95% CIs. RESULTS AND CONCLUSION: The available evidence of the treatment of COVID-19 with traditional Chinese medicine will be summarized, and evaluation of the efficacy and the adverse effects of these treatments will be made. This review will be disseminated in print by peer-review.
has issue date	2020-06-19(xsd:dateTime)
bibo:doi	10.1097/md.0000000000020660
bibo:pmid	32569196
has license	cc-by
sha1sum (hex)	d07701d7148b836f6b66dd2a99550754ab17031c
schema:url	https://doi.org/10.1097/md.0000000000020660
resource representing a document's title	Chinese medicine for COVID-19: A protocol for systematic review and meta-analysis
has PubMed Central identifier	PMC7310886
has PubMed identifier	32569196
schema:publication	Medicine (Baltimore)
resource representing a document's body	covid:d07701d7148b836f6b66dd2a99550754ab17031c#body_text
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