About: Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study

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About: Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study
Creator	Beganton, Frankie Bougouin, Wulfran Derkenne, Clément Frattini, Benoit Jost, Daniel Jouven, Xavier Karam, Nicole Lafont, Antoine Marijon, Eloi Narayanan, Kumar Perrot, David Sharifzadehgan, Ardalan Waldmann, Victor
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Although mortality due to COVID-19 is, for the most part, robustly tracked, its indirect effect at the population level through lockdown, lifestyle changes, and reorganisation of health-care systems has not been evaluated. We aimed to assess the incidence and outcomes of out-of-hospital cardiac arrest (OHCA) in an urban region during the pandemic, compared with non-pandemic periods. METHODS: We did a population-based, observational study using data for non-traumatic OHCA (N=30 768), systematically collected since May 15, 2011, in Paris and its suburbs, France, using the Paris Fire Brigade database, together with in-hospital data. We evaluated OHCA incidence and outcomes over a 6-week period during the pandemic in adult inhabitants of the study area. FINDINGS: Comparing the 521 OHCAs of the pandemic period (March 16 to April 26, 2020) to the mean of the 3052 total of the same weeks in the non-pandemic period (weeks 12–17, 2012–19), the maximum weekly OHCA incidence increased from 13·42 (95% CI 12·77–14·07) to 26·64 (25·72–27·53) per million inhabitants (p<0·0001), before returning to normal in the final weeks of the pandemic period. Although patient demographics did not change substantially during the pandemic compared with the non-pandemic period (mean age 69·7 years [SD 17] vs 68·5 [18], 334 males [64·4%] vs 1826 [59·9%]), there was a higher rate of OHCA at home (460 [90·2%] vs 2336 [76·8%]; p<0·0001), less bystander cardiopulmonary resuscitation (239 [47·8%] vs 1165 [63·9%]; p<0·0001) and shockable rhythm (46 [9·2%] vs 472 [19·1%]; p<0·0001), and longer delays to intervention (median 10·4 min [IQR 8·4–13·8] vs 9·4 min [7·9–12·6]; p<0·0001). The proportion of patients who had an OHCA and were admitted alive decreased from 22·8% to 12·8% (p<0·0001) in the pandemic period. After adjustment for potential confounders, the pandemic period remained significantly associated with lower survival rate at hospital admission (odds ratio 0·36, 95% CI 0·24–0·52; p<0·0001). COVID-19 infection, confirmed or suspected, accounted for approximately a third of the increase in OHCA incidence during the pandemic. INTERPRETATION: A transient two-times increase in OHCA incidence, coupled with a reduction in survival, was observed during the specified time period of the pandemic when compared with the equivalent time period in previous years with no pandemic. Although this result might be partly related to COVID-19 infections, indirect effects associated with lockdown and adjustment of health-care services to the pandemic are probable. Therefore, these factors should be taken into account when considering mortality data and public health strategies. FUNDING: The French National Institute of Health and Medical Research (INSERM)
has issue date	2020-05-27(xsd:dateTime)
bibo:doi	10.1016/s2468-2667(20)30117-1
bibo:pmid	32473113
has license	no-cc
sha1sum (hex)	d07598c88fca7bcbfbd49722cc4b1fd61d30088d
schema:url	https://doi.org/10.1016/s2468-2667%2820%2930117-1
resource representing a document's title	Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study
has PubMed Central identifier	PMC7255168
has PubMed identifier	32473113
schema:publication	Lancet Public Health
resource representing a document's body	covid:d07598c88fca7bcbfbd49722cc4b1fd61d30088d#body_text
is schema:about of	named entity 'Background' named entity 'observational study' named entity 'pandemic' named entity 'HEALTH' named entity 'COVID-19' named entity 'cardiac arrest' named entity 'France' named entity 'observational study' named entity 'cough' named entity 'COVID' named entity 'triage' named entity 'Paris' named entity 'OHCA' named entity 'medical services' named entity 'advanced life support' named entity 'COVID' named entity 'EMS' named entity 'cardiac arrest' named entity 'OHCA' named entity 'COVID' named entity 'COVID' named entity 'health-care' named entity 'EMS' named entity 'Paris' named entity 'OHCA' named entity 'Lombardy' named entity 'COVID' named entity 'Paris' named entity 'March 17' named entity 'COVID-19' named entity 'COVID' named entity 'OHCA' named entity 'dyspnoea' named entity 'Paris' named entity 'COVID-19 pandemic' named entity 'suboptimal health' named entity 'cardiopulmonary resuscitation' named entity 'Paris' named entity 'infection' named entity 'Paris' named entity 'Paris' named entity 'emergency medical services' named entity 'R software' named entity 'personal protective equipment' named entity 'sudden death' named entity 'health-care systems' named entity 'infection' named entity 'emergency responders' named entity 'Paris' named entity 'observational study' named entity 'OHCA' named entity 'COVID-19' named entity 'cardiac arrest' named entity 'OHCA' named entity 'OHCA' named entity 'COVID' named entity 'public behaviour' named entity 'regression analysis' named entity 'OHCA' named entity 'OHCA' named entity 'OHCA' named entity 'OHCA' named entity 'Kruskal-Wallis test' named entity 'COVID' named entity 'regression analysis' named entity 'cardiac arrest' named entity 'Italy' named entity 'personal protective equipment' named entity 'EMS'

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