About: Early Cardiac Allograft Vasculopathy: Are the Viruses to Blame?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Early Cardiac Allograft Vasculopathy: Are the Viruses to Blame?
Creator	Aggarwal, Ashim Bhat, Geetha Hamilton, John Pyle, Joseph
Source	Medline; PMC
abstract	This paper describes a case of early (7 months after transplant) cardiac allograft vasculopathy. This-43-year-old (CMV positive, EBV negative) female patient underwent an orthotopic heart transplant with a (CMV negative, EBV positive) donor heart. She had a history of herpes zoster infection and postherpetic neuralgia in the past. The patient's panel reactive antibodies had been almost undetectable on routine surveillance testing, and her surveillance endomyocardial biopsies apart from a few episodes of mild-to-moderate acute cellular rejection (treated adequately with steroids) never showed any evidence of humoral rejection. The postoperative course was complicated by multiple admissions for upper respiratory symptoms, and the patient tested positive for entero, rhino, and coronaviruses serologies. During her last admission (seven months postoperatively) the patient developed mild left ventricular dysfunction with an ejection fraction of 40%. The patient's endomyocardial biopsy done at that time revealed concentric intimal proliferation and inflammation resulting in near-total luminal occlusion in the epicardial and the intramyocardial coronary vessels, suggestive of graft vasculopathy with no evidence of rejection, and the patient had a fatal ventricular arrhythmia.
has issue date	2012-05-31(xsd:dateTime)
bibo:doi	10.1155/2012/734074
bibo:pmid	22701124
has license	cc-by
sha1sum (hex)	cd9f8fa1af71d9ebded8173ef9d8a6a6aab05207
schema:url	https://doi.org/10.1155/2012/734074
resource representing a document's title	Early Cardiac Allograft Vasculopathy: Are the Viruses to Blame?
has PubMed Central identifier	PMC3369528
has PubMed identifier	22701124
schema:publication	Case Rep Med
resource representing a document's body	covid:cd9f8fa1af71d9ebded8173ef9d8a6a6aab05207#body_text
is schema:about of	named entity 'testing' named entity 'graft' named entity 'concentric' named entity 'upper' named entity 'fatal' named entity 'heart' named entity 'Viruses' named entity 'VASCULOPATHY' named entity 'INTIMAL PROLIFERATION' named entity 'CORONAVIRUSES' named entity 'ACUTE CELLULAR REJECTION' named entity 'ANTIBODIES' named entity 'STEROIDS' named entity 'ORTHOTOPIC' named entity 'EBV NEGATIVE' named entity 'GRAFT' named entity 'OCCLUSION' named entity 'POSTOPERATIVE COURSE' named entity 'SURVEILLANCE' named entity 'FEMALE PATIENT' named entity 'HERPES ZOSTER INFECTION' named entity 'HUMORAL REJECTION' named entity 'REJECTION' named entity 'NEVER' named entity 'TOTAL' named entity 'RESPIRATORY SYMPTOMS' named entity 'SEROLOGIES' named entity 'EBV POSITIVE' named entity 'occlusion' named entity 'undetectable' named entity 'evidence' named entity 'proliferation' named entity 'positive' named entity 'endomyocardial biopsy' named entity 'describes' named entity 'cellular' named entity 'Case' named entity 'cardiac allograft vasculopathy' named entity 'endomyocardial biopsy' named entity 'intimal' named entity 'graft' named entity 'steroids' named entity 'EBV' named entity 'antibodies' named entity 'coronary vessels' named entity 'case' named entity 'dyslipidemia' named entity 'intravenous antibiotics' named entity 'viral infections' named entity 'serologically' named entity 'pathogen' named entity 'cellular immune' named entity 'hyperlipidemia' named entity 'atherosclerosis' named entity 'cardiac transplant' named entity 'EBV' named entity 'Viral infections' named entity 'risk factor' named entity 'postherpetic neuralgia' named entity 'dilated cardiomyopathy' named entity 'heart failure' named entity 'coronary artery disease' named entity 'lipid' named entity 'CAV' named entity 'pathogens' named entity 'CAV' named entity 'pseudomonas' named entity 'CAV' named entity 'pathogens' named entity 'transesophageal echocardiogram' named entity 'antiviral treatment' named entity 'malignancy' named entity 'infection' named entity 'Epstein-Barr' named entity 'CMV' named entity 'prophylaxis' named entity 'morbidity' named entity 'abdominal pain'

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