About: The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China
Creator	Chang, Christopher Jiang, Taijiao Guan, Kai Peng, Fujun Sun, Jinlyu Wang, Runsheng Xu, Guogang Yang, Yongshi
Source	Elsevier; Medline; PMC
abstract	Abstract The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. This viral epidemic in China has led to the deaths of over 1800 people, mostly elderly or those with an underlying chronic disease or immunosuppressed state. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003 and MERS in 2012. While human strains of Coronavirus are associated with about 15% of cases of the common cold, the SARS-CoV-2 may present with varying degrees of severity, from flu-like symptoms to death. It is currently believed that this deadly Coronavirus strain originated from wild animals at the Huanan market in Wuhan, a city in Hubei province. Bats, snakes and pangolins have been cited as potential carriers based on the sequence homology of CoV isolated from these animals and the viral nucleic acids of the virus isolated from SARS-CoV-2 infected patients. Extreme quarantine measures, including sealing off large cities, closing borders and confining people to their homes, were instituted in January 2020 to prevent spread of the virus, but by that time much of the damage had been done, as human-human transmission became evident. While these quarantine measures are necessary and have prevented a historical disaster along the lines of the Spanish flu, earlier recognition and earlier implementation of quarantine measures may have been even more effective. Lessons learned from SARS resulted in faster determination of the nucleic acid sequence and a more robust quarantine strategy. However, it is clear that finding an effective antiviral and developing a vaccine are still significant challenges. The costs of the epidemic are not limited to medical aspects, as the virus has led to significant sociological, psychological and economic effects globally. Unfortunately, emergence of SARS-CoV-2 has led to numerous reports of Asians being subjected to racist behavior and hate crimes across the world.
has issue date	2020-03-03(xsd:dateTime)
bibo:doi	10.1016/j.jaut.2020.102434
bibo:pmid	32143990
has license	els-covid
sha1sum (hex)	cd4f5118038ae33283d34a15f8c3888f00e247bc
schema:url	https://doi.org/10.1016/j.jaut.2020.102434
resource representing a document's title	The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China
has PubMed Central identifier	PMC7126544
has PubMed identifier	32143990
schema:publication	J Autoimmun
resource representing a document's body	covid:cd4f5118038ae33283d34a15f8c3888f00e247bc#body_text
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