About: Emergence of enterovirus 71 “double-recombinant” strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71

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About: Emergence of enterovirus 71 “double-recombinant” strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Emergence of enterovirus 71 “double-recombinant” strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71
Creator	Chan, Kwok-Hung Tsoi, Hoi-Wah Zhou, Boping Yip, Cyril Lau, Susanna Woo, Patrick Yuen, Yung Zhang, Ming-Xia Chen, • Xin-Chun Kwok, •
Source	Medline; PMC
abstract	Hand–foot–mouth disease due to enterovirus 71 (EV71) and coxsackievirus A16 (CA16) has recently caused large outbreaks in mainland China in 2008. We performed complete genome sequencing on two EV71 (SZ/HK08-5 and SZ/HK08-6) and two CA16 (SZ/HK08-3 and SZ/HK08-7) strains from patients in Shenzhen, China. Phylogenetic, similarity plot and bootscan analyses revealed recombination between EV71 genotypes B and C at the 2A–2B junction, and between EV71 genotype B and CA16 strain G-10 in the 3C region for EV71 strains. A similar phenomenon was also found upon further gene sequencing with other EV71 strains. Recombination between CA16 strain G-10 and EV71 genotype A at the 2A–2B junction was also observed for CA16 strains. The present “double-recombinant” EV71 strains circulating in China and other EV71 subgenotype “C4” strains represent an additional genotype, D. CA16 strains should also be classified into two genotypes. This represents the first evidence for a combination of intratypic and intertypic recombination in EV71 strains. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-010-0722-0) contains supplementary material, which is available to authorized users.
has issue date	2010-06-13(xsd:dateTime)
bibo:doi	10.1007/s00705-010-0722-0
bibo:pmid	20549263
has license	no-cc
sha1sum (hex)	cd1d16026918b8902146adec8012af4fc7095ff1
schema:url	https://doi.org/10.1007/s00705-010-0722-0
resource representing a document's title	Emergence of enterovirus 71 “double-recombinant” strains belonging to a novel genotype D originating from southern China: first evidence for combination of intratypic and intertypic recombination events in EV71
has PubMed Central identifier	PMC7087135
has PubMed identifier	20549263
schema:publication	Arch Virol
resource representing a document's body	covid:cd1d16026918b8902146adec8012af4fc7095ff1#body_text
is schema:about of	named entity 'China' named entity 'strains' named entity 'analyses' named entity 'recombination' named entity 'genotype' named entity 'strains' named entity 'China' named entity 'GENOTYPE' named entity 'CHINA' named entity 'DISEASE DUE TO ENTEROVIRUS' named entity 'GENE SEQUENCING' covid:arg/cd1d16026918b8902146adec8012af4fc7095ff1 named entity 'STRAINS' named entity 'REGION' named entity 'RECENTLY' named entity 'FOUND' named entity 'PHENOMENON' named entity 'COMBINATION' named entity 'RECOMBINATION' named entity 'SOUTHERN' named entity 'NOVEL' named entity 'GENOTYPE' named entity 'CIRCULATING' named entity 'COMBINATION' named entity 'ENTEROVIRUS 71' named entity 'PRESENT' named entity 'EMERGENCE' named entity 'EVIDENCE FOR' named entity 'RECOMBINANT' named entity 'REPRESENT' named entity 'PERFORMED' named entity 'STRAIN' named entity 'GENOTYPES' named entity 'REVEALED' named entity 'HAND-FOOT-MOUTH DISEASE' named entity 'LARGE' named entity 'OUTBREAKS' named entity 'EVIDENCE FOR' named entity 'ADDITIONAL' named entity 'MAINLAND CHINA' named entity 'BELONGING' named entity 'COXSACKIEVIRUS A16' named entity 'CHINA' named entity 'PATIENTS' named entity 'JUNCTION' named entity 'PLOT' named entity 'SIMILARITY' named entity 'STRAINS' named entity 'CLASSIFIED' named entity 'COMPLETE GENOME SEQUENCING' named entity 'OBSERVED' named entity 'EVENTS' named entity 'RECOMBINATION' named entity 'ENTEROVIRUS 71' named entity 'CAUSED' named entity 'RECOMBINANT' named entity 'A16' named entity 'G-10' named entity 'strains' named entity 'enterovirus' named entity 'strains' named entity 'mainland China' named entity 'Shenzhen' named entity 'recombination' named entity 'genotypes' named entity 'China' named entity 'EV71' named entity 'enterovirus 71' named entity 'nucleotide sequences' named entity 'nucleotide' named entity 'clinical features' named entity 'HFMD'

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