About: Neurological Consequences of 2019-nCoV Infection: A Comprehensive Literature Review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Neurological Consequences of 2019-nCoV Infection: A Comprehensive Literature Review
Creator	Azim, Dua Hussain, Azhar Kumar, Sohail Nasim, Sundus Patel, Sundip
Source	Medline; PMC
abstract	First identified in November 2019 in Hubei Province, the coronavirus disease of 2019 (COVID-19) caused by SARS-CoV-2 soon spread worldwide to become a global health pandemic. The COVID-19 preferentially damages the respiratory system that produces symptoms such as fever, cough, and shortness of breath. However, the infection often tends to disseminate to involve various organ systems. Recent evidence indicates that SARS-CoV-2 can cause significant neurological damage and resultant neurological symptoms and complications. Here, we provide a comprehensive and thorough review of original articles, case reports, and case series to delineate the possible mechanisms of nervous system invasion and damage by SARS-CoV-2 and subsequent consequences. We divided the neurological manifestations into three categories: (1) Central Nervous System involvement, (2) Peripheral Nervous System manifestations, and (3) Skeletal Muscle Injury. Headache and dizziness were found to be the most prevalent symptoms followed by impaired consciousness. Among the symptoms indicating peripheral nervous system invasion, anosmia and dysgeusia were commonly reported. Skeletal muscle injury predominantly presents as myalgia. In addition, encephalitis, myelitis, cerebrovascular disease, Guillain-Barre syndrome, and Miller Fischer syndrome were among the commonly noted complications. We also emphasized the association of pre-existing comorbidities with neurological manifestations. The aim of this review is to provide a deeper understanding of the potential neurological implications to help neurologists have a high index of clinical suspicion allowing them to manage the patient appropriately.
has issue date	2020-06-24(xsd:dateTime)
bibo:doi	10.7759/cureus.8790
bibo:pmid	32601577
has license	cc-by
sha1sum (hex)	cbe62b8c1b0618cdd4038e17f2a5ec0481903a4d
schema:url	https://doi.org/10.7759/cureus.8790
resource representing a document's title	Neurological Consequences of 2019-nCoV Infection: A Comprehensive Literature Review
has PubMed Central identifier	PMC7317136
has PubMed identifier	32601577
schema:publication	Cureus
resource representing a document's body	covid:cbe62b8c1b0618cdd4038e17f2a5ec0481903a4d#body_text
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