About: Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines
Creator	Kaiser, Laurent Siegrist, Claire-Anne Bescher-Ninet, Béatrice Bille, Jacques Cevey-Macherel, Manon Galetto-Lacour, Annick Gehri, Mario Gervaix, Alain Krahenbuhl, Jean-Daniel
Source	Medline; PMC
abstract	Community-acquired pneumonia (CAP) is a major cause of death in developing countries and of morbidity in developed countries. The objective of the study was to define the causative agents among children hospitalized for CAP defined by WHO guidelines and to correlate etiology with clinical severity and surrogate markers. Investigations included an extensive etiological workup. A potential causative agent was detected in 86% of the 99 enrolled patients, with evidence of bacterial (53%), viral (67%), and mixed (33%) infections. Streptococcus pneumoniae was accounted for in 46% of CAP. Dehydration was the only clinical sign associated with bacterial pneumonia. CRP and PCT were significantly higher in bacterial infections. Increasing the number of diagnostic tests identifies potential causes of CAP in up to 86% of children, indicating a high prevalence of viruses and frequent co-infections. The high proportion of pneumococcal infections re-emphasizes the importance of pneumococcal immunization.
has issue date	2009-02-24(xsd:dateTime)
bibo:doi	10.1007/s00431-009-0943-y
bibo:pmid	19238436
has license	no-cc
sha1sum (hex)	cbaed0d63ffb2ec547ba00d33503996ef7495d46
schema:url	https://doi.org/10.1007/s00431-009-0943-y
resource representing a document's title	Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines
has PubMed Central identifier	PMC7087130
has PubMed identifier	19238436
schema:publication	Eur J Pediatr
resource representing a document's body	covid:cbaed0d63ffb2ec547ba00d33503996ef7495d46#body_text
is schema:about of	named entity 'causative' named entity 'hospitalized' named entity 'Etiology' covid:arg/cbaed0d63ffb2ec547ba00d33503996ef7495d46 named entity 'surrogate' named entity 'patients' named entity 'CAP' named entity 'define' named entity 'Community-acquired pneumonia' named entity 'clinical sign' named entity 'viruses' named entity 'developing countries' named entity 'extensive' named entity 'Dehydration' named entity 'diagnostic tests' named entity 'causative agent' named entity 'CAP' named entity 'viruses' named entity 'pneumococcal infections' named entity 'bacterial pneumonia' named entity 'viruses' named entity 'antibody' named entity 'Parainfluenza' named entity 'wheezing' named entity 'RT-PCR' named entity 'bacterial pneumonia' named entity 'CRP' named entity 'titer' named entity 'Influenza' named entity 'PCR analysis' named entity 'etiology' named entity 'blood sample' named entity 'Mycoplasma pneumoniae' named entity 'diagnostic method' named entity 'viral pneumonia' named entity 'pneumonia' named entity 'viruses' named entity 'sensitivity and specificity' named entity 'pneumococcal' named entity '21%' named entity 'non-parametric statistical tests' named entity 'clarithromycin' named entity 'viruses' named entity 'Adenovirus' named entity 'WHO' named entity 'wheezing' named entity 'Influenza' named entity 'pleural fluid' named entity 'WHO' named entity 'WHO' named entity 'inflammatory' named entity 'gene' named entity 'viral pneumonia' named entity 'enterovirus' named entity 'lysis buffer' named entity 'Taqman' named entity 'clinical sign' named entity 'cefuroxime' named entity 'PCR' named entity 'viral infection' named entity 'real-time PCR' named entity 'antibiotics' named entity 'viral infection' named entity 'coagulase-negative Staphylococci' named entity 'upper respiratory tract' named entity 'diagnostic tools' named entity 'Kappa coefficient' named entity 'viral infection' named entity 'pathogens' named entity '37°C' named entity 'pneumococcal' named entity 'Taqman' named entity 'S. pneumoniae'

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