About: Deleted in colorectal cancer (netrin‐1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis

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About: Deleted in colorectal cancer (netrin‐1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Deleted in colorectal cancer (netrin‐1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis
Creator	Uchida, Kazuyuki Matsunaga, Satoru Fukata, Yuko Hasegawa, Daisuke Nakanishi, Akio Ohnishi, Yumi Ohtani, Shouhei Yokoi, Norihiko Chambers, James Fukata, \| Koyama, \| Shiga, \|
Source	Medline; PMC
abstract	A 7‐year‐old neutered female domestic shorthaired cat born in Poland and then moved to Japan presented to the local clinic with recent onset of convulsive cluster seizures and status epilepticus. Magnetic resonance imaging revealed bilateral swelling of the hippocampus with T2 hyperintensity and contrast enhancing image, suggesting hippocampal necrosis. The cat completely recovered after treatment with antiepileptic drugs (AED) and administration of prednisolone (1 mg/kg PO q24h for 4 days and tapered). However, cluster seizures reoccurred and developed into status epilepticus despite increasing doses of AED. Although the convulsions were resolved by other AEDs, stupor and renal failure developed, and the cat was euthanized. Pathological findings were consistent with hippocampal necrosis. Immunological analysis for leucine‐rich glioma inactivated 1 (LGI1) autoantibodies was negative, but antibodies against DCC (deleted in colorectal carcinoma) known as netrin‐1 receptor were found. This report describes a case of feline autoimmune limbic encephalitis and hippocampal necrosis that were presumably associated with DCC autoantibodies.
has issue date	2019-04-03(xsd:dateTime)
bibo:doi	10.1111/jvim.15492
bibo:pmid	30942925
has license	cc-by-nc
sha1sum (hex)	ca274e20fd535ce3666baf7a70daffcecd68d5ae
schema:url	https://doi.org/10.1111/jvim.15492
resource representing a document's title	Deleted in colorectal cancer (netrin‐1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis
has PubMed Central identifier	PMC6524083
has PubMed identifier	30942925
schema:publication	J Vet Intern Med
resource representing a document's body	covid:ca274e20fd535ce3666baf7a70daffcecd68d5ae#body_text
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