About: Engineering self-assembled materials to study and direct immune function

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Engineering self-assembled materials to study and direct immune function Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Engineering self-assembled materials to study and direct immune function
Creator	Jewell, Christopher Tostanoski, Lisa
Source	Elsevier; Medline; PMC
abstract	Abstract The immune system is an awe-inspiring control structure that maintains a delicate and constantly changing balance between pro-immune functions that fight infection and cancer, regulatory or suppressive functions involved in immune tolerance, and homeostatic resting states. These activities are determined by integrating signals in space and time; thus, improving control over the densities, combinations, and durations with which immune signals are delivered is a central goal to better combat infectious disease, cancer, and autoimmunity. Self-assembly presents a unique opportunity to synthesize materials with well-defined compositions and controlled physical arrangement of molecular building blocks. This review highlights strategies exploiting these capabilities to improve the understanding of how precisely-displayed cues interact with immune cells and tissues. We present work centered on fundamental properties that regulate the nature and magnitude of immune response, highlight pre-clinical and clinical applications of self-assembled technologies in vaccines, cancer, and autoimmunity, and describe some of the key manufacturing and regulatory hurdles facing these areas.
has issue date	2017-05-15(xsd:dateTime)
bibo:doi	10.1016/j.addr.2017.03.005
bibo:pmid	28392305
has license	els-covid
sha1sum (hex)	c89186e7b4d0b8533280c31a29b87d931c1e8d06
schema:url	https://doi.org/10.1016/j.addr.2017.03.005
resource representing a document's title	Engineering self-assembled materials to study and direct immune function
has PubMed Central identifier	PMC6262758
has PubMed identifier	28392305
schema:publication	Advanced Drug Delivery Reviews
resource representing a document's body	covid:c89186e7b4d0b8533280c31a29b87d931c1e8d06#body_text
is schema:about of	named entity 'facing' named entity 'autoimmunity' named entity 'highlights' named entity 'unique' named entity 'immune tolerance' named entity 'delicate' named entity 'Engineering' named entity 'immune function' named entity 'LICENSE' named entity 'MAGNITUDE' named entity 'REGULATE' named entity 'IMMUNE SYSTEM' named entity 'PROPERTIES' named entity 'DESCRIBE' named entity 'UNDERSTANDING' named entity 'AUTOIMMUNITY' named entity 'BETTER' named entity 'IMMUNE CELLS' named entity 'HOMEOSTATIC' named entity 'FIGHT' named entity 'STRATEGIES' named entity 'IMMUNE' named entity 'NC-' named entity 'DIRECT' named entity 'INTEGRATING' named entity 'COMBINATIONS' named entity 'CHANGING BALANCE' named entity 'KEY' named entity 'DETERMINED BY' named entity 'IMMUNE RESPONSE' named entity 'INTERACT' named entity 'ORG' named entity 'ENGINEERING' named entity 'SELF' named entity 'STUDY' named entity 'IMMUNE FUNCTION' named entity 'MANUFACTURING' named entity 'SIGNALS' named entity 'DELIVERED' named entity 'AWE' named entity 'RESTING' named entity 'CANCER' named entity 'IMPROVING' named entity 'COMPOSITIONS' named entity 'CLINICAL' named entity 'CONTROLLED' named entity 'CENTRAL' named entity 'OPPORTUNITY' named entity 'AREAS' named entity 'INVOLVED' named entity 'MATERIALS' named entity 'INFECTIOUS DISEASE' named entity 'PRESENT' named entity 'PHYSICAL' named entity 'NATURE' named entity 'WELL-DEFINED' named entity 'IS A' named entity 'MATERIALS' named entity 'DURATIONS' named entity 'ACTIVITIES' named entity 'UNIQUE' named entity 'MOLECULAR' named entity 'PRO-' named entity 'IMMUNE TOLERANCE' named entity 'SUPPRESSIVE' named entity 'INFECTION' named entity 'CONTROL' named entity 'HOW' named entity 'SPACE AND TIME' named entity 'THESE' named entity 'FUNCTIONS' named entity 'SELF' named entity 'VACCINES' named entity 'STATES' named entity 'CUES' named entity 'ARRANGEMENT' named entity 'WORK' named entity 'PRE-CLINICAL' named entity 'TECHNOLOGIES' named entity 'TISSUES'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software