About: Smell dysfunction in COVID-19 patients: More than a yes-no question

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Smell dysfunction in COVID-19 patients: More than a yes-no question
Creator	Silva, T Araujo, Abelardo Azevedo, Anna Chagas, Ingrid Espíndola, Otávio Leite, Ana Lima, Marco Moraes, Raissa Oliveira, Raquel Rezende, Rafaela Soares, Cristiane Takano, Crissi Tulius, Marcus
Source	Elsevier; PMC
abstract	Anosmia has been recognized as a prevalent and early symptom by many COVID-19 patients. However, most researchers have recorded smell dysfunction solely as present or absent and based on subjective evaluation by patients. We described the results of 57 consecutive COVID-19 patients seen at FIOCRUZ, Rio de Janeiro, Brazil, from April to May 2020. Data about the presence of smell loss, the onset of smell loss and other COVID-19 symptoms such as ageusia and nasal congestion or rhinorrhea were recorded. All patients at the initial consultation and 34 healthy controls underwent the Q-SIT, which is a quick disposable three-item smell identification test, by a trained physician. We compared three groups: healthy controls, COVID+ patients with reported smell loss (COVID w/ SL) and COVID+ patients without smell loss (COVID+ w/o SL). The mean age of patients was 41.4 years (SD ± 10.4), and 54.4% were women. Smell loss was reported by 40.4% of COVID-19 patients. We observed a gradual effect with higher Q-SIT scores in healthy controls, followed by COVID+ w/o SL and COVID+ w/ SL (medians = 3, 2 and 0; respectively, p < 0.001). Anosmia or severe microsmia (Q-SIT≤1) was present in 11.1% (CI: 3.1%–26.1%) of controls, 32.4% (CI: 17.4%–50.5%) of COVID-19 w/o SL and 87% (CI: 66.4%–97.2%) of COVID+ w/ SL (p < 0.001). This study provides evidence that olfactory dysfunction in COVID-19 is common and more prevalent than what is perceived by patients. Q-SIT is a quick and reliable screening test for the detection of smell dysfunction during the pandemics.
has issue date	2020-11-15(xsd:dateTime)
bibo:doi	10.1016/j.jns.2020.117107
has license	no-cc
sha1sum (hex)	c88b97d23fcabe06448efdc6575e3d3925ab0d17
schema:url	https://doi.org/10.1016/j.jns.2020.117107
resource representing a document's title	Smell dysfunction in COVID-19 patients: More than a yes-no question
has PubMed Central identifier	PMC7449134
schema:publication	J Neurol Sci
resource representing a document's body	covid:c88b97d23fcabe06448efdc6575e3d3925ab0d17#body_text
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