About: Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China

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About: Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China
Creator	Yang, Yi Yao, Ying Xu, Gang Wang, Yanan Zhou, Xi He, Fan Li, Junhua Ge, Shuwang Pan, Hao Cheng, Anying Guo, Shuiming Ning, Yong Shi, Jia Xing, Xue Chang, Xiaoyan Gong, Meiling Xiao, Fang
Source	PMC
abstract	INTRODUCTION: Maintenance hemodialysis (MHD) patients are highly vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Medical staff of dialysis facilities without sufficient biosecurity protection are susceptible once exposed to asymptomatic coronavirus disease 2019 (COVID-19) patients. This study evaluated the epidemiological characteristics of COVID-19 in all MHD patients and medical staff of dialysis facilities in Wuhan, China. METHODS: We collected COVID-19 morbidity and mortality data from MHD patients and medical staff from 52 hemodialysis centers in Wuhan. Then, we analyzed the symptoms and signs of patients and staff in our hospital (Tongji Hospital in Wuhan), and chest CT, SARS-CoV-2 nucleic acid detection and laboratory tests were performed. After aggressive quarantine of the COVID-19 patients, we followed up on the prognosis of them. RESULTS: We analyzed the hemodialysis data from Wuhan and found that 10% of MHD patients and 6.0% of medical staff were suspected of COVID-19. Further detection of SARS-CoV-2 nucleic acid showed that 1.7% of MHD patients and 2.9% of medical staff were confirmed as having COVID-19. In our facility, 18.9% (46/244) of patients and 9.5% (6/63) of medical staff were suspected of COVID-19. Among them, 2.9% (7/244) of MHD patients and 4.8% (3/63) of medical staff tested positive for SARS-CoV-2 were confirmed as having COVID-19. Interestingly, 87.0% of MHD patients suspected of COVID-19 did not have obvious symptoms, but the CT screening showed features of viral pneumonia. There were no significant differences in symptoms, CT findings, comorbidity and laboratory findings of SARS-CoV-2 nucleic-acid-positive and -negative patients. We followed up these patients and found that 57 patients with COVID-19 died (COVID-19 mortality 8.9%). Two patients from our dialysis center with COVID-19 (mortality 4.3%) died. No new infections occurred in our dialysis center after aggressive quarantine was initiated. CONCLUSIONS: The SARS-CoV-2 infection rates in MHD patients and medical staff in dialysis facilities were both high in Wuhan. Frequent chest CT and SARS-CoV-2 nucleic acid detection were needed to screen COVID-19 patients in dialysis facilities. Through the lessons of this experience on the aggressive diagnosis and quarantine measures of COVID-19 patients, we hope medical staff avoid more infections in serious epidemic areas.
has issue date	2020-05-25(xsd:dateTime)
bibo:doi	10.1159/000508579
has license	cc-by-nc-nd
sha1sum (hex)	c8536bae20b1929705d8e95b16955bc85d6ef4e0
schema:url	https://doi.org/10.1159/000508579
resource representing a document's title	Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China
has PubMed Central identifier	PMC7316663
schema:publication	Kidney Dis (Basel)
resource representing a document's body	covid:c8536bae20b1929705d8e95b16955bc85d6ef4e0#body_text
is schema:about of	named entity 'quarantine' named entity 'suspected' named entity 'patients' named entity 'patients' named entity 'MHD' named entity 'epidemic' named entity 'Results' named entity 'comorbidity' named entity 'COVID-19' named entity 'detection' named entity 'signs' named entity 'measures' named entity 'Patients' named entity 'COVID-19' named entity 'STUDY' named entity 'DID' named entity 'MORTALITY DATA' named entity 'CENTERS' named entity '2.9' named entity 'HIGH' named entity 'CHEST CT' named entity 'RATES' named entity 'COVID-19' named entity 'CHINA' named entity 'detection' named entity 'mortality' named entity 'COVID-19' named entity 'laboratory tests' named entity 'died' named entity 'patients' named entity 'data' named entity 'high' named entity 'acid' named entity 'chest' named entity 'detection' named entity 'Medical' named entity 'COVID-19' named entity 'dialysis' named entity 'patients' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'Two' named entity 'Wuhan' named entity 'medical staff' named entity 'Wuhan' named entity 'medical staff' named entity 'nucleic acid detection' named entity 'SARS-CoV-2' named entity 'hemodialysis' named entity 'medical staff' named entity 'medical staff' named entity 'viral pneumonia' named entity 'COVID-19' named entity 'epidemic' named entity 'nucleic acid' named entity 'COVID' named entity 'laboratory tests' named entity 'biosecurity' named entity 'Tongji Hospital' named entity 'medical staff' named entity 'morbidity' named entity 'SARS-CoV-2' named entity 'Hemodialysis' named entity 'Wuhan' named entity 'Hemodialysis' named entity 'This' named entity 'COVID-19'

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