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| - OBJECTIVE: We aimed to observe the clinical characteristics of coronavirus disease 2019 (COVID‐19) patients with overweight and obesity. METHODS: Consecutive COVID‐19 patients from 10 hospitals of Jiangsu province, China were enrolled. RESULTS: 297 COVID‐19 patients were included. 39.39% and 13.47% of patients were overweight and obese, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P=0.033) and type 2 diabetes (17.50% vs. 3.57%, P=0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P=0.006) and obesity (25.00% vs. 2.86%, P<0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P<0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P=0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P=0.029). Overweight (OR 4.222, 95%CI 1.322‐13.476, P=0.015) and obesity (OR 9.216, 95% CI 2.581‐32.903, P=0.001) were independent risk factors of severe illness. Obesity (HR 6.607, 95% CI 1.955‐22.329, P=0.002) was an independent risk factor of respiratory failure. CONCLUSION: Overweight and obesity were independent risk factors of severe illness in COVID‐19 patients. More attention should be paid to these patients.
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