About: Assessment of SARS-CoV-2 in human semen

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Assessment of SARS-CoV-2 in human semen - a cohort study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Assessment of SARS-CoV-2 in human semen - a cohort study
Creator	Petra, Ba, Petra Bielfeld, Alexandra Cornelius, Doehmen Doehmen, Dunja B-B, Cornelius Dunja Baston-Buest, Dunja, Baston-Buest Holtmann, Nora Jan-Steffen, Kruessel Marcel, Andree Nora, Holtmann Ortwin, Adams Petra, Alexandra Philippos, Edimiris
Source	Medline; PMC
abstract	OBJECTIVE: To investigate the presence of viral RNA in human semen of severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) recovered and positive patients and to evaluate its presence and relevance on semen parameters. DESIGN: Pilot cohort study SETTING: University hospital PATIENTS: 34 adult males were distributed into a) patients in convalescence (patients with confirmed SARS-CoV-2 infection in pharyngeal swab by RT-PCR and/or antibodies), b) negative control group (no antibodies) and c) patients with an acute infection (detection of SARS-CoV-2 in pharyngeal swab). INTERVENTION: Semen and a blood sample were collected from each individual. MAIN OUTCOME MEASURES: Analysis of semen quality according to the WHO standards. Detection of SARS-CoV-2 by RT-PCR in the native semen sample and after density gradient preparation. Confirmation of Immunoglobulin (Ig)-A und Ig-G antibodies in the blood. RESULTS: 18 semen samples from recovered males were obtained 8 to 54 days after absence of symptoms, 14 samples from controls and 2 samples from patients with an active COVID-19 infection. No RNA was detected by RT-PCR in the semen including semen samples from two patients with an acute COVID-19 infection. Subjects with a moderate infection showed an impairment of sperm quality. CONCLUSION: A mild COVID-19 infection is not likely to affect testis and epididymis function, whereas semen parameters did seem impaired after a moderate infection . SARS-CoV-2 RNA could not be detected in semen of recovered and acute COVID-19 positive males. This suggests no viral transmission during sexual contact and assisted reproductive techniques (ART), however, further data need to be obtained.
has issue date	2020-05-29(xsd:dateTime)
bibo:doi	10.1016/j.fertnstert.2020.05.028
bibo:pmid	32650948
has license	no-cc
sha1sum (hex)	c7a1ccbf36656b156946ba870d37e448ffc07bd2
schema:url	https://doi.org/10.1016/j.fertnstert.2020.05.028
resource representing a document's title	Assessment of SARS-CoV-2 in human semen - a cohort study
has PubMed Central identifier	PMC7256599
has PubMed identifier	32650948
schema:publication	Fertil Steril
resource representing a document's body	covid:c7a1ccbf36656b156946ba870d37e448ffc07bd2#body_text
is schema:about of	named entity 'SARS-CoV-2' named entity 'patients' named entity 'semen' named entity 'Sterility' named entity 'semen' named entity 'STERILITY' named entity 'COVID-19' named entity 'RECOVERED' named entity 'INFECTED' named entity 'PATIENTS' covid:arg/c7a1ccbf36656b156946ba870d37e448ffc07bd2 named entity 'male fertility' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'semen' named entity 'cohort study' named entity 'semen' named entity 'viral infections' named entity 'male fertility' named entity 'angiotensin converting enzyme' named entity 'SARS CoV' named entity 'COVID-19' named entity 'semen' named entity 'sensitivity and specificity' named entity 'sperm' named entity 'SARS-CoV-2' named entity 'semen' named entity 'pneumonia' named entity 'SARS-CoV-2' named entity 'infection' named entity 'urine' named entity 'Germany' named entity 'male reproductive' named entity 'testis' named entity 'fatigue' named entity 'paracetamol' named entity 'viral transmission' named entity 'infection' named entity 'COVID' named entity 'viruses' named entity 'RNA extraction' named entity 'COVID' named entity 'Malden, Netherlands' named entity 'Sperm morphology' named entity 'ejaculation' named entity 'ACE2' named entity 'male reproductive tract' named entity 'Germany' named entity 'infertility' named entity 'IgG' named entity 'body ache' named entity 'sperm quality' named entity 'WHO' named entity 'endotracheal intubation' named entity 'COVID' named entity 'male fertility' named entity 'sperm' named entity 'coronavirus 2' named entity 'IgA' named entity 'statistical significant' named entity 'fever' named entity 'nasopharyngeal' named entity 'testis' named entity 'COVID-19' named entity 'testis' named entity 'RT-PCR'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software