About: Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis

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About: Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis
Creator	Beltran, E Crawford, A Fraser, A Michaels, J Sanchez-Masian, D Shea, A Stoll, A
source	Medline; PMC
abstract	BACKGROUND: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Information regarding the magnetic resonance imaging (MRI) findings of neurologic FIP currently is limited, resulting in the need for better descriptions to optimize its use as a diagnostic tool. OBJECTIVE: To describe the clinicopathologic features and MRI findings in cases of confirmed neurologic FIP. ANIMALS: Twenty‐four client‐owned cats with histopathologic confirmation of neurologic FIP. METHODS: Archived records from 5 institutions were retrospectively reviewed to identify cases with confirmed neurologic FIP that had undergone antemortem MRI of the CNS. Signalment, clinicopathologic, MRI, and histopathologic findings were evaluated. RESULTS: Three distinct clinical syndromes were identified: T3‐L3 myelopathy (3), central vestibular syndrome (7), and multifocal CNS disease (14). Magnetic resonance imaging abnormalities were detected in all cases, including meningeal contrast enhancement (22), ependymal contrast enhancement (20), ventriculomegaly (20), syringomyelia (17), and foramen magnum herniation (14). Cerebrospinal fluid was analysed in 11 cases; all demonstrated a marked increase in total protein concentration and total nucleated cell count. All 24 cats were euthanized with a median survival time of 14 days (range, 2–115) from onset of clinical signs. Histopathologic analysis identified perivascular pyogranulomatous infiltrates, lymphoplasmacytic infiltrates, or both affecting the leptomeninges (16), choroid plexuses (16), and periventricular parenchyma (13). CONCLUSIONS AND CLINICAL IMPORTANCE: Magnetic resonance imaging is a sensitive means of detecting neurologic FIP, particularly in combination with a compatible signalment, clinical presentation, and CSF analysis.
has issue date	2017-08-19(xsd:dateTime)
bibo:doi	10.1111/jvim.14791
bibo:pmid	28833469
has license	cc-by-nc
sha1sum (hex)	c7a16d3975bbb4ad4f44786d1e5961d16d21f863
schema:url	https://doi.org/10.1111/jvim.14791
resource representing a document's title	Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis
has PubMed Central identifier	PMC5598904
has PubMed identifier	28833469
schema:publication	J Vet Intern Med
resource representing a document's body	covid:c7a16d3975bbb4ad4f44786d1e5961d16d21f863#body_text
is schema:about of	named entity 'Confirmed' named entity 'FINDINGS' named entity 'INFECTIOUS' named entity 'RESULTING IN' named entity 'FIP' named entity 'IMPROVED' named entity 'LIMITED' named entity 'FATAL' named entity 'NEED FOR' named entity 'CENTRAL NERVOUS SYSTEM' named entity 'ANTEMORTEM DIAGNOSIS' named entity 'MAGNETIC RESONANCE IMAGING' named entity 'CLINICOPATHOLOGIC FEATURES' named entity 'FELINE INFECTIOUS PERITONITIS' named entity 'FINDINGS' named entity 'MAGNETIC RESONANCE IMAGING' named entity 'NEUROLOGIC' named entity 'CATS' named entity 'DESCRIPTIONS' named entity 'DIAGNOSTIC TOOL' named entity 'FELINE INFECTIOUS PERITONITIS' named entity 'OPTIMIZE' named entity 'INFORMATION' named entity 'MEANS' named entity 'DISEASE' named entity 'COMMON' named entity 'ITS' named entity 'CONFIRMED' named entity 'USE' named entity 'BACKGROUND' named entity 'CAT' named entity 'NEUROLOGIC' named entity 'CLINICAL DECISION MAKING' named entity 'REQUIRED' named entity 'CURRENTLY' named entity 'BETTER' covid:arg/c7a16d3975bbb4ad4f44786d1e5961d16d21f863 named entity 'Information' named entity 'Background' named entity 'central nervous system (CNS)' named entity 'CNS' named entity 'magnetic resonance imaging' named entity 'Feline infectious peritonitis' named entity 'central nervous' named entity 'diagnostic tool' named entity 'Feline Infectious Peritonitis' named entity 'Histopathologically' named entity 'Neurologic' named entity 'pleocytosis' named entity 'mass effect' named entity 'ventriculomegaly' named entity 'clinical presentation' named entity 'parenchyma' named entity 'contrast enhancement' named entity 'central canal' named entity 'lesion' named entity 'biochemistry' named entity 'cerebellum' named entity 'ataxia' named entity 'ventriculomegaly' named entity 'neurologic' named entity 'euthanasia' named entity 'lateral' named entity 'meningoencephalitis' named entity 'interthalamic adhesion' named entity 'rabies' named entity 'systemic disease' named entity 'Syringomyelia' named entity 'histopathologic' named entity 'brainstem' named entity 'ventricles' named entity 'protein' named entity 'lateral ventricles' named entity 'decreased white blood cell count' named entity 'rectal temperature'

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