About: Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling

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About: Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling
Creator	Ehlen, Thomas Follen, Michelle Marra, Marco Miller, Dianne Richards-Kortum, Rebecca Jones, Steven Kneller, Julie Lam, Wan Macaulay, Calum Matisic, Jasenka Niekerk, Dirk
Source	Medline; PMC
abstract	Sixteen longSAGE libraries from four different clinical stages of cervical intraepithelial neoplasia have enabled us to identify novel cell-surface biomarkers indicative of CIN stage. By comparing gene expression profiles of cervical tissue at early and advanced stages of CIN, several genes are identified to be novel genetic markers. We present fifty-six cell-surface gene products differentially expressed during progression of CIN. These cell surface proteins are being examined to establish their capacity for optical contrast agent binding. Contrast agent visualization will allow real-time assessment of the physiological state of the disease process bringing vast benefit to cancer care. The data discussed in this publication have been submitted to NCBIs Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) and are accessible through GEO Series accession number GSE6252.
has issue date	2007-12-11(xsd:dateTime)
bibo:pmid	19662225
has license	cc-by
sha1sum (hex)	c77f37d083293f7461d47471caa670e765270948
resource representing a document's title	Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling
has PubMed Central identifier	PMC2717845
has PubMed identifier	19662225
schema:publication	Biomark Insights
resource representing a document's body	covid:c77f37d083293f7461d47471caa670e765270948#body_text
is schema:about of	named entity 'tissue' named entity 'surface' named entity 'cervical intraepithelial neoplasia' named entity 'CIN' named entity 'EARLY' named entity 'LES' named entity 'ALLOW' named entity 'PRESENT' named entity 'NIH' named entity 'CIN' named entity 'SERIES' named entity 'BEING' named entity 'ACCESSION NUMBER' named entity 'GENE EXPRESSION' named entity 'NCBI' named entity 'HAVE' named entity 'EXPRESSED' named entity 'DIFFERENT' named entity 'PUBLICATION' named entity 'CERVICAL INTRAEPITHELIAL NEOPLASIA' named entity 'STAGE' named entity 'CLINICAL STAGES' named entity 'VISUALIZATION' named entity 'DISEASE PROCESS' named entity 'CELL' named entity 'CERVICAL' named entity 'TO IDENTIFY' named entity 'THESE' named entity 'REAL-TIME' named entity 'CELL SURFACE' named entity 'SUBMITTED' named entity 'BINDING' named entity 'GOV' named entity 'CONTRAST AGENT' named entity 'ESTABLISH' named entity 'GENES' named entity 'THEIR' named entity 'ADVANCED' named entity 'GEO' named entity 'CONTRAST AGENT' named entity 'LABELLING' named entity 'USING' named entity 'TISSUE' named entity 'AMENABLE' named entity 'OPTICAL' named entity 'TO DETECT' named entity 'BIOMARKERS' named entity 'CANCER CARE' named entity 'GENE' named entity 'HTTP' named entity 'SURFACE' named entity 'PRODUCTS' named entity 'LIBRARIES' named entity 'STAGES' named entity 'PHYSIOLOGICAL STATE' named entity 'SURFACE PROTEINS' named entity 'BIOMARKERS' named entity 'CERVICAL CANCER' named entity 'COMPARING' named entity 'DATA' named entity 'EXAMINED' named entity 'NLM' named entity 'GENETIC MARKERS' named entity 'ASSESSMENT' named entity 'OPTICAL' named entity 'CAPACITY' named entity 'ACCESSIBLE' named entity 'NOVEL' named entity 'ENABLED' named entity 'PROGRESSION' named entity 'SIXTEEN' covid:arg/c77f37d083293f7461d47471caa670e765270948 named entity 'contrast agent'

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