About: Proteomic analysis by iTRAQ in red claw crayfish, Cherax quadricarinatus, hematopoietic tissue cells post white spot syndrome virus infection

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About: Proteomic analysis by iTRAQ in red claw crayfish, Cherax quadricarinatus, hematopoietic tissue cells post white spot syndrome virus infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Proteomic analysis by iTRAQ in red claw crayfish, Cherax quadricarinatus, hematopoietic tissue cells post white spot syndrome virus infection
Creator	Jeswin, Joseph Ji, Qiao-Lin Liu, Hai-Peng Wang, Ke-Jian Xie, Xiao-Lu
Source	Elsevier; Medline; PMC
abstract	To elucidate proteomic changes of Hpt cells from red claw crayfish, Cherax quadricarinatus, we have carried out isobaric tags for relative and absolute quantitation (iTRAQ) of cellular proteins at both early (1 hpi) and late stage (12 hpi) post white spot syndrome virus (WSSV) infection. Protein database search revealed 594 protein hits by Mascot, in which 17 and 30 proteins were present as differentially expressed proteins at early and late viral infection, respectively. Generally, these differentially expressed proteins include: 1) the metabolic process related proteins in glycolysis and glucogenesis, DNA replication, nucleotide/amino acid/fatty acid metabolism and protein biosynthesis; 2) the signal transduction related proteins like small GTPases, G-protein-alpha stimulatory subunit, proteins bearing PDZ- or 14-3-3-domains that help holding together and organize signaling complexes, casein kinase I and proteins of the MAP-kinase signal transduction pathway; 3) the immune defense related proteins such as α-2 macroglobulin, transglutaminase and trans-activation response RNA-binding protein 1. Taken together, these protein information shed new light on the host cellular response against WSSV infection in a crustacean cell culture.
has issue date	2016-02-01(xsd:dateTime)
bibo:doi	10.1016/j.fsi.2016.01.035
bibo:pmid	26845698
has license	no-cc
sha1sum (hex)	c6ee7a7a69e09890468e829369f3c3e8434a7f23
schema:url	https://doi.org/10.1016/j.fsi.2016.01.035
resource representing a document's title	Proteomic analysis by iTRAQ in red claw crayfish, Cherax quadricarinatus, hematopoietic tissue cells post white spot syndrome virus infection
has PubMed Central identifier	PMC7111676
has PubMed identifier	26845698
schema:publication	Fish Shellfish Immunol
resource representing a document's body	covid:c6ee7a7a69e09890468e829369f3c3e8434a7f23#body_text
is schema:about of	named entity 'HEMATOPOIETIC TISSUE' named entity 'RED' named entity 'CELLS' named entity 'transglutaminase' named entity 'claw' named entity 'Proteomic' named entity 'PROTEIN ' named entity 'HOLDING' named entity 'SUBUNIT' named entity 'GENERALLY' named entity 'MASCOT' named entity 'GLUCOGENESIS' named entity 'SIGNAL TRANSDUCTION' named entity 'CLAW' named entity 'ACTIVATION' named entity 'CARRIED' named entity 'RED' named entity 'DNA REPLICATION' named entity 'INFECTION' named entity 'CASEIN KINASE I' named entity 'EARLY' named entity 'LIKE' named entity 'TRANS' named entity 'CRAYFISH' named entity 'TAKEN' named entity 'INCLUDE' named entity 'CELLS' named entity 'NUCLEOTIDE' named entity 'VIRAL INFECTION' named entity 'MACROGLOBULIN' named entity 'ALPHA' named entity 'DATABASE SEARCH' named entity 'MAP' named entity 'KINASE' named entity 'POST' named entity 'DEFENSE' named entity 'PRESENT' named entity 'NEW' named entity 'CHANGES' named entity 'CRUSTACEAN' named entity 'ISOBARIC TAGS FOR RELATIVE AND ABSOLUTE QUANTITATION' named entity 'SIGNALING COMPLEXES' named entity 'HPI' named entity 'PROTEOMIC' named entity 'GLYCOLYSIS' named entity 'AND LATE' named entity 'PROTEINS' named entity 'WSSV' named entity 'CELLULAR' named entity 'THESE' named entity 'LATE STAGE' named entity 'EXPRESSED' named entity 'PROTEIN DATABASE' named entity 'INFORMATION' named entity 'G-PROTEIN' named entity 'SMALL' named entity 'PDZ' named entity 'BINDING PROTEIN' named entity 'VIRUS INFECTION' named entity 'CRAYFISH' named entity 'ITRAQ' named entity 'PROTEOMIC ANALYSIS' named entity 'CLAW' named entity 'HITS' named entity 'ORGANIZE' named entity 'CELLULAR RESPONSE' named entity 'HAVE' named entity 'CHERAX QUADRICARINATUS' named entity 'CELL CULTURE' named entity 'BEARING' named entity 'METABOLIC PROCESS' named entity 'IMMUNE' named entity 'LIGHT' named entity 'REVEALED' named entity 'TRANSGLUTAMINASE' named entity 'HPT' named entity 'A-2'

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