About: The pathogens profile in children with otitis media with effusion and adenoid hypertrophy

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About: The pathogens profile in children with otitis media with effusion and adenoid hypertrophy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The pathogens profile in children with otitis media with effusion and adenoid hypertrophy
Creator	Arruda, E Anselmo-Lima, W Buzatto, G Carenzi, L Gagliardi, T Hyppolito, M Massuda, E Prates, M Proenca-Modena, J Saturno, T Tamashiro, E Valera, F
topic	covid:c6bfe832f2dd36a5c86f548138c96883ce0f46b7#this
source	Medline; PMC
abstract	OBJECTIVES: To evaluate the presence of viruses and bacteria in middle ear and adenoids of patients with and without otitis media with effusion (OME). METHODS: Adenoid samples and middle ear washes (MEW) were obtained from children with OME associated with adenoid hypertrophy undergoing adenoidectomy and tympanostomy, and compared to those obtained from patients undergoing cochlear implant surgery, as a control group. Specific DNA or RNA of 9 respiratory viruses (rhinovirus, influenza virus, picornavirus, syncytial respiratory virus, metapneumovirus, coronavirus, enterovirus, adenovirus and bocavirus) and 5 bacteria (S. pneumoniae, H. influenzae, M. catarrhalis, P. aeruginosa and S. aureus) were extracted and quantified by real-time PCR. RESULTS: 37 OME and 14 cochlear implant children were included in the study. At the adenoid, virus and bacteria were similarly detected in both OME and control patients. At the middle ear washes, however, a higher prevalence of bacteria was observed in patients with OME (p = 0.01). S. pneumoniae (p = 0.01) and M. catarrhalis (p = 0.022) were the bacteria responsible for this difference. Although total virus detection was not statistically different from controls at the middle ear washes (p = 0.065), adenovirus was detected in higher proportions in adenoid samples of OME patients than controls (p = 0.019). CONCLUSIONS: Despite both OME and control patients presented similar rates of viruses and bacteria at the adenoid, children with OME presented higher prevalence of S. pneumonia, M. catarrhalis in middle ear and adenovirus in adenoids when compared to controls. These findings could suggest that these pathogens could contribute to the fluid persistence in the middle ear.
has issue date	2017-02-23(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0171049
bibo:pmid	28231295
has license	cc-by
sha1sum (hex)	c6bfe832f2dd36a5c86f548138c96883ce0f46b7
schema:url	https://doi.org/10.1371/journal.pone.0171049
resource representing a document's title	The pathogens profile in children with otitis media with effusion and adenoid hypertrophy
has PubMed Central identifier	PMC5322954
has PubMed identifier	28231295
schema:publication	PLoS One
resource representing a document's body	covid:c6bfe832f2dd36a5c86f548138c96883ce0f46b7#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/c6bfe832f2dd36a5c86f548138c96883ce0f46b7
is schema:about of	named entity 'adenoids' named entity 'evaluate' named entity 'pathogens' named entity 'CHILDREN' named entity 'EVALUATE' named entity 'PATHOGENS' named entity 'OTITIS MEDIA WITH EFFUSION' covid:arg/c6bfe832f2dd36a5c86f548138c96883ce0f46b7 named entity 'PROFILE' named entity 'ADENOID HYPERTROPHY' named entity 'MIDDLE EAR' named entity 'PATIENTS' named entity 'OTITIS MEDIA WITH EFFUSION' named entity 'PRESENCE OF' named entity 'BACTERIA ' named entity 'VIRUSES' named entity 'ADENOIDS' named entity 'otitis media' named entity 'adenoid' named entity 'adenoids' named entity 'viruses' named entity 'pathogens' named entity 'adenoid hypertrophy' named entity 'viruses' named entity 'influenza virus' named entity 'environmental factors' named entity 'viruses' named entity '0.01' named entity 'antimicrobial agents' named entity 'adenoid hypertrophy' named entity 'viral infection' named entity 'adenoid' named entity 'adenoid' named entity 'bacteria' named entity 'pneumococcal' named entity 'CD4+' named entity 'Eustachian tube' named entity 'microbiology' named entity 'antimycotic' named entity 'microbes' named entity 'viruses' named entity 'adenoid' named entity 'adenoid' named entity 'pathogenesis' named entity 'adenoids' named entity 'Trizol' named entity 'middle ear' named entity 'S. pneumoniae' named entity 'adenoids' named entity 'middle ear' named entity 'chronic inflammatory' named entity 'adenoid' named entity 'control patients' named entity 'middle ear' named entity 'adenoid' named entity 'punch biopsy' named entity 'middle ear' named entity '0.01' named entity 'mucosal surfaces' named entity 'enterovirus' named entity 'microbiota' named entity 'microbial' named entity 'bacteria' named entity 'control patients' named entity 'dysphagia' named entity 'nucleic acid' named entity 'Otitis media with effusion' named entity 'rhinovirus'

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