About: A lung rescue team improves survival in obesity with acute respiratory distress syndrome

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: A lung rescue team improves survival in obesity with acute respiratory distress syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A lung rescue team improves survival in obesity with acute respiratory distress syndrome
Creator	Lai, Yvonne Wiener-Kronish, Jeanine Berra, Lorenzo Kacmarek, Robert Pinciroli, Riccardo Amato, Marcelo Arora, Pankaj Bagchi, Aranya Berg, Sheri Bittner, Edward Ferrari, Matteo Florio, Gaetano Fumagalli, Jacopo Hibbert, Kathryn Kuo, Alexander Kwo, Jean Lai, Peggy Mietto, Cristina Pino, Richard Pirrone, Massimiliano Shelton, Kenneth Sonny, Abraham De, Roberta Santiago, Santis Droghi, Maddalena
Source	Medline; PMC
abstract	BACKGROUND: Limited data exist regarding ventilation in patients with class III obesity [body mass index (BMI) > 40 kg/m(2)] and acute respiratory distress syndrome (ARDS). The aim of the present study was to determine whether an individualized titration of mechanical ventilation according to cardiopulmonary physiology reduces the mortality in patients with class III obesity and ARDS. METHODS: In this retrospective study, we enrolled adults admitted to the ICU from 2012 to 2017 who had class III obesity and ARDS and received mechanical ventilation for > 48 h. Enrolled patients were divided in two cohorts: one cohort (2012–2014) had ventilator settings determined by the ARDSnet table for lower positive end-expiratory pressure/higher inspiratory fraction of oxygen (standard protocol-based cohort); the other cohort (2015–2017) had ventilator settings determined by an individualized protocol established by a lung rescue team (lung rescue team cohort). The lung rescue team used lung recruitment maneuvers, esophageal manometry, and hemodynamic monitoring. RESULTS: The standard protocol-based cohort included 70 patients (BMI = 49 ± 9 kg/m(2)), and the lung rescue team cohort included 50 patients (BMI = 54 ± 13 kg/m(2)). Patients in the standard protocol-based cohort compared to lung rescue team cohort had almost double the risk of dying at 28 days [31% versus 16%, P = 0.012; hazard ratio (HR) 0.32; 95% confidence interval (CI95%) 0.13–0.78] and 3 months (41% versus 22%, P = 0.006; HR 0.35; CI95% 0.16–0.74), and this effect persisted at 6 months and 1 year (incidence of death unchanged 41% versus 22%, P = 0.006; HR 0.35; CI95% 0.16–0.74). CONCLUSION: Individualized titration of mechanical ventilation by a lung rescue team was associated with decreased mortality compared to use of an ARDSnet table. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13054-019-2709-x) contains supplementary material, which is available to authorized users.
has issue date	2020-01-15(xsd:dateTime)
bibo:doi	10.1186/s13054-019-2709-x
bibo:pmid	31937345
has license	cc-by
sha1sum (hex)	c6781e2907c505c15a8f82b97bcf4062f6301545
schema:url	https://doi.org/10.1186/s13054-019-2709-x
resource representing a document's title	A lung rescue team improves survival in obesity with acute respiratory distress syndrome
has PubMed Central identifier	PMC6961369
has PubMed identifier	31937345
schema:publication	Crit Care
resource representing a document's body	covid:c6781e2907c505c15a8f82b97bcf4062f6301545#body_text
is schema:about of	named entity 'cohort' named entity 'mechanical ventilation' named entity 'persisted' named entity 'obesity' named entity 'hazard ratio' named entity 'recruitment' named entity 'Methods' named entity 'rescue' named entity 'oxygen' named entity 'lung' named entity 'team' named entity '2014' named entity 'rescue' named entity 'cohort' named entity 'dying' named entity 'rescue' named entity 'patients' named entity 'patients' named entity 'Patients' named entity '2015' named entity 'double' named entity 'body' named entity 'lung' named entity 'obesity' named entity '2017' named entity 'class III' named entity 'class III' named entity 'body mass index' named entity 'positive end-expiratory pressure' named entity 'incidence of death' named entity 'lung' named entity 'ARDS' named entity 'BMI' named entity 'mechanical ventilation' named entity 'comorbidities' named entity 'ICU' named entity 'class III' named entity 'obesity' named entity 'respiratory mechanics' named entity 'rescue group' named entity 'obesity' named entity 'titration' named entity 'BMI' named entity 'ARDS' named entity 'ICU' named entity 'ICU' named entity 'mechanical ventilation' named entity 'alveoli' named entity 'ICU' named entity 'critically ill patients' named entity 'APACHE' named entity 'metastatic cancer' named entity 'BMI' named entity 'ARDS' named entity 'mortality rate' named entity 'follow-up' named entity 'ARDS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software