About: Community Respiratory Viruses in Individuals with Human Immunodeficiency Virus Infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Community Respiratory Viruses in Individuals with Human Immunodeficiency Virus Infection
Creator	King, James
Source	Elsevier; Medline; PMC
abstract	Abstract Respiratory viruses, particularly influenza viruses, respiratory syncytial virus (RSV), parainfluenza viruses, and adenoviruses, are ubiquitous pathogens among humans, especially among young children. However, relatively little is known about the impact of these common infections on individuals with the human immunodeficiency virus (HIV). A review of the literature identifies three key areas that need further exploration. First, moderate-to-severe and even fatal lower respiratory viral illnesses in HIV-infected individuals have been reported. In general, the clinical presentation of these respiratory viral infections in persons with HIV infection is similar to their presentation in individuals without HIV infection. The major exception is the occurrence of fulminant, and often fatal, disseminated adenovirus infection in adults and children with HIV disease. Despite these reports, no information is available regarding the frequency of moderate-to-severe respiratory viral illnesses in individuals with HIV infection. Epidemiologic studies of respiratory viral illnesses in cohorts of HIV-infected adults and children are needed. Second, prolonged shedding of respiratory viruses for weeks and even months has been documented in HIV-infected adults and children. The frequency of prolonged shedding in this population has not been well defined, but data from a small newborn cohort study suggest that, at least for RSV, prolonged shedding is common. Prolonged respiratory viral shedding has implications for infection control in medical facilities where HIV-infected individuals are treated and in nursing homes, child care centers, and group foster homes that provide care for HIV-infected individuals. Therapies to help eliminate these chronic viral infections should be explored. Finally, indirect evidence suggests that respiratory viral infection may result in changes in HIV replication and, theoretically, HIV disease progression. Increased HIV-1 replication has been demonstrated in vitro in T lymphoma cells exposed to genetic material from adenovirus. Increased HIV replication in peripheral blood from adults following inactivated influenza vaccination has been reported. The impact of natural respiratory viral infection (and perhaps vaccination against these pathogens) on HIV replication and disease progression will be an important area of study.
has issue date	1997-03-17(xsd:dateTime)
bibo:doi	10.1016/s0002-9343(97)80005-8
bibo:pmid	10868138
has license	els-covid
sha1sum (hex)	c6568dd2c4fdc50f1614e96ed78f5fe37f3180ed
schema:url	https://doi.org/10.1016/s0002-9343%2897%2980005-8
resource representing a document's title	Community Respiratory Viruses in Individuals with Human Immunodeficiency Virus Infection
has PubMed Central identifier	PMC7119403
has PubMed identifier	10868138
schema:publication	The American Journal of Medicine
resource representing a document's body	covid:c6568dd2c4fdc50f1614e96ed78f5fe37f3180ed#body_text
is schema:about of	named entity 'parainfluenza' named entity 'adenoviruses' named entity 'First' named entity 'RESPIRATORY VIRUSES' named entity 'FATAL' named entity 'ADENOVIRUSES' named entity 'ABOUT' named entity 'KEY' named entity 'AREAS' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'COMMON' named entity 'THESE' named entity 'HUMAN IMMUNODEFICIENCY VIRUS' named entity 'LOWER' named entity 'INDIVIDUALS' named entity 'EXPLORATION' named entity 'PARAINFLUENZA' named entity 'RESPIRATORY' named entity 'KNOWN' named entity 'HUMANS' named entity 'RESPIRATORY VIRUSES' named entity 'INFLUENZA VIRUSES' named entity 'INFECTIONS' named entity 'VIRUSES' named entity 'VIRAL' named entity 'YOUNG CHILDREN' named entity 'MODERATE-TO-SEVERE' named entity 'INDIVIDUALS' named entity 'HUMAN IMMUNODEFICIENCY VIRUS INFECTION' named entity 'COMMUNITY' named entity 'ILLNESSES' named entity 'LITTLE' named entity 'NEED' named entity 'REVIEW OF THE LITERATURE' named entity 'UBIQUITOUS' named entity 'IMPACT' named entity 'PATHOGENS' named entity 'Respiratory' named entity 'Infection' named entity 'influenza viruses' named entity 'respiratory syncytial virus' named entity 'HIV' named entity 'viruses' named entity 'Human Immunodeficiency Virus Infection' named entity 'virus' named entity 'viruses' named entity 'parainfluenza' named entity 'disseminated disease' named entity 'measles' named entity 'viruses' named entity 'respiratory viral infections' named entity 'influenza' named entity 'infection control' named entity 'HIV' named entity 'respiratory tract infections' named entity 'HIV' named entity 'serum' named entity 'pathogen' named entity 'Influenza' named entity 'viral shedding' named entity 'day care centers' named entity 'RSV infection' named entity 'HIV infection' named entity 'infection control' named entity 'parainfluenza' named entity 'HIV' named entity 'co-infected' named entity 'antigenic' named entity 'general population' named entity 'HIV' named entity 'respiratory viral infections' named entity 'viruses' named entity 'immune deficiencies' named entity 'viral infections' named entity 'CMV' named entity 'HIV' named entity 'HIV' named entity 'case reports' named entity 'HIV disease' named entity 'human immunodeficiency virus' named entity 'HIV disease'

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