About: Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients
Creator	Blanc, Raphael Ciccio, Gabriele Delvoye, François Desilles, Jean-Philippe Escalard, Simon Hébert, Solène Mazighi, Mikael Maïer, Benjamin Piotin, Michel Redjem, Hocine Smajda, Stanislas Chalumeau, Vanessa Escalard, Clément
Source	Medline; PMC
abstract	BACKGROUND AND PURPOSE: Reports are emerging regarding the association of acute ischemic strokes with large vessel occlusion and coronavirus disease 2019 (COVID-19). While a higher severity of these patients could be expected from the addition of both respiratory and neurological injury, COVID-19 patients with strokes can present with mild or none respiratory symptoms. We aimed to compare anterior circulation large vessel occlusion strokes severity between patients with and without COVID-19. METHODS: We performed a comparative cohort study between patients with COVID-19 who had anterior circulation large vessel occlusion and early brain imaging within 3 hours from onset, in our institution during the 6 first weeks of the COVID-19 outbreak and a control group admitted during the same calendar period in 2019. RESULTS: Twelve COVID-19 patients with anterior circulation large vessel occlusion and early brain imaging were included during the study period and compared with 34 control patients with anterior circulation large vessel occlusion and early brain imaging in 2019. Patients in the COVID-19 group were younger (P=0.032) and had a history of diabetes mellitus more frequently (P=0.039). Patients did not significantly differ on initial National Institutes of Health Stroke Scale nor time from onset to imaging (P=0.18 and P=0.6, respectively). Patients with COVID-19 had more severe strokes than patients without COVID-19, with a significantly lower clot burden score (median: 6.5 versus 8, P=0.016), higher rate of multivessel occlusion (50% versus 8.8%, P=0.005), lower DWI-ASPECTS (Diffusion-Weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores; median: 5 versus 8, P=0.006), and higher infarct core volume (median: 58 versus 6 mL, P=0.004). Successful recanalization rate was similar in both groups (P=0.767). In-hospital mortality was higher in the COVID-19 patients’ group (41.7% versus 11.8%, P=0.025). CONCLUSIONS: Early brain imaging showed higher severity large vessel occlusion strokes in patients with COVID-19. Given the massive number of infected patients, concerns should be raised about the coming neurovascular impact of the pandemic worldwide.
has issue date	2020-08-19(xsd:dateTime)
bibo:doi	10.1161/strokeaha.120.031011
bibo:pmid	32813602
has license	no-cc
sha1sum (hex)	c5a6be9c18ad17126295db0da2fa9e26b2ea1117
schema:url	https://doi.org/10.1161/strokeaha.120.031011
resource representing a document's title	Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients
has PubMed Central identifier	PMC7446979
has PubMed identifier	32813602
schema:publication	Stroke
resource representing a document's body	covid:c5a6be9c18ad17126295db0da2fa9e26b2ea1117#body_text
is schema:about of	named entity 'Large' named entity 'Ischemic' named entity 'COVID-19' named entity 'current literature' named entity 'stroke patients' named entity 'thrombectomy' named entity 'ischemic strokes' named entity 'COVID-19' named entity 'early diagnosis' named entity 'stroke patients' named entity 'COVID-19' named entity 'thrombolysis' named entity 'vessel occlusion' named entity 'endothelial dysfunction' named entity 'coagulation disorders' named entity 'real-time polymerase chain reaction' named entity 'brain imaging' named entity 'COVID-19' named entity 'infarct' named entity 'diffusion-weighted imaging' named entity 'Stroke' named entity 'COVID-19' named entity 'cohort study' named entity 'brain imaging' named entity 'vessel occlusion' named entity 'coronavirus disease 2019' named entity 'vessel occlusion' named entity 'middle cerebral artery' named entity 'thrombolysis' named entity 'COVID-19' named entity 'COVID-19' named entity 'extrapulmonary' named entity 'COVID-19' named entity 'vessel occlusion' named entity 'ischemic stroke' named entity 'neurological injury' named entity 'systemic inflammation' named entity 'COVID-19' named entity 'respiratory infection' named entity 'posterior cerebral artery' named entity 'COVID-19' named entity 'informed consent' named entity 'infarct' named entity 'anonymized data' named entity 'real-time polymerase chain reaction' named entity 'infarct' named entity 'thrombectomy' named entity 'stroke' named entity 'Food and Drug Administration' named entity 'COVID-19' named entity 'coronavirus disease 2019' named entity 'COVID-19' named entity 'clinical care' named entity 'decision-making' named entity 'prognosis' named entity 'Geneva' named entity 'COVID-19' named entity 'thrombotic complications' named entity 'respiratory symptoms' named entity 'stroke' named entity 'COVID-19' named entity 'COVID-19' named entity 'significance level' named entity 'Mann-Whitney U test' named entity 'Osirix' named entity 'United States' named entity 'Fisher exact test' named entity 'COVID-19' named entity 'COVID-19'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software