About: Effects of intravenously infused Fluosol-DA 20% in rats

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of intravenously infused Fluosol-DA 20% in rats
Creator	Gendler, Simona Seymour, Christine West, Laurie Wisdom, Charlene And, B Mcintosh, Norma
Source	Elsevier; Medline; PMC
abstract	Abstract Rats were injected with a fractionated 50 ml/kg dose of Fluosol®-DA 20% with and without exposure to 100% oxygen. Animals were killed at 24, 43, 92, and 183 days post-treatment and samples taken for hematological, hepatic enzyme, histological, and perfluorochemical analyses. There were no significant differences in hemograms or hepatic enzyme findings between treatment and control groups. Differences in organ weights and histology were a result of perfluorochemical (PFC) accumulation in the tissues of treated animals. All changes were reversible. There were no effects from breathing high oxygen levels in either treatment or control animals.
has issue date	1986-08-31(xsd:dateTime)
bibo:doi	10.1016/0360-3016(86)90163-x
bibo:pmid	3759552
has license	els-covid
sha1sum (hex)	c4c5a6fd756afc5414847e5f83feb0478117db04
schema:url	https://doi.org/10.1016/0360-3016%2886%2990163-x
resource representing a document's title	Effects of intravenously infused Fluosol-DA 20% in rats
has PubMed Central identifier	PMC7131096
has PubMed identifier	3759552
schema:publication	International Journal of Radiation OncologyBiologyPhysics
resource representing a document's body	covid:c4c5a6fd756afc5414847e5f83feb0478117db04#body_text
is schema:about of	named entity 'days' named entity 'high' named entity 'injected' named entity 'dose' named entity 'accumulation' named entity 'INTRAVENOUSLY' named entity 'OXYGEN' named entity '100%' named entity 'SIGNIFICANT' named entity 'TREATMENT' named entity 'SAMPLES' named entity 'FLUOSOL' named entity 'PERFLUOROCHEMICAL' named entity 'CONTROL' named entity 'HEMATOLOGICAL' named entity 'EFFECTS' named entity 'RATS' named entity '20%' named entity 'FLUOSOL-DA' named entity 'CHANGES' named entity 'EITHER' named entity '20%' named entity 'TISSUES' named entity 'HISTOLOGICAL' named entity '183' named entity 'HISTOLOGY' named entity 'HEPATIC ENZYME' named entity 'EXPOSURE TO' named entity 'EFFECTS' named entity 'BREATHING' named entity 'ORGAN WEIGHTS' named entity 'FINDINGS' named entity 'FRACTIONATED' named entity 'DAYS' named entity 'KILLED' named entity 'RATS' named entity 'CONTROL GROUPS' named entity 'POST-TREATMENT' named entity 'ANIMALS' named entity 'HIGH' named entity 'REVERSIBLE' named entity 'LEVELS' named entity 'DOSE' named entity 'TREATED' named entity 'ACCUMULATION' named entity 'RESULT' named entity 'TAKEN' covid:arg/c4c5a6fd756afc5414847e5f83feb0478117db04 named entity 'Oxygen' named entity 'Fluosol' named entity 'mycoplasmosis' named entity 'perfluorochemical' named entity 'weight gain' named entity 'SGPT' named entity 'hypoxic' named entity 'Histological examination' named entity 'mycoplasma' named entity 'Light microscopic' named entity 'macrophage' named entity 'SGOT' named entity 'lung' named entity 'spleen' named entity 'organ' named entity 'radiosensitizing agent' named entity '1.6' named entity 'fibroid' named entity 'depression' named entity 'liver' named entity 'Tissue samples' named entity 'adverse effects' named entity 'All' named entity 'PFC' named entity 'organ' named entity 'hepatic' named entity 'enzyme' named entity 'Fluosol'

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