About: The infant airway microbiome in health and disease impacts later asthma development

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The infant airway microbiome in health and disease impacts later asthma development Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The infant airway microbiome in health and disease impacts later asthma development
Creator	Gern, James Grindle, Kristine Hollams, Elysia Inouye, Michael Kusel, Merci Mok, Danny Pham, Kym Serralha, Michael Troy, Niamh Johnston, Sebastian Bochkov, Yury Hales, Belinda Holt, Barbara Holt, Kathryn Holt, Patrick Sly, Peter Teo, Shu Walker, Michael
Source	BioRxiv; MedRxiv
abstract	The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory illnesses (ARI). The development of asthma is initiated during infancy, driven by airway inflammation associated with infections. Here, we report viral and bacterial community profiling of NP aspirates across a birth cohort, capturing all lower respiratory illnesses during their first year. Most infants were initially colonized with Staphylococcus or Corynebacterium before stable colonization with Alloiococcus or Moraxella, with transient incursions of Streptococcus, Moraxella or Haemophilus marking virus-associated ARIs. Our data identify the NP microbiome as a determinant for infection spread to the lower airways, severity of accompanying inflammatory symptoms, and risk for future asthma development. Early asymptomatic colonization with Streptococcus was a strong asthma predictor, and antibiotic usage disrupted asymptomatic colonization patterns.
has issue date	2014-12-02(xsd:dateTime)
bibo:doi	10.1101/012070
has license	medrxiv
sha1sum (hex)	c41fdb2efd6d61384a92a84cbba3f8233629a41b
schema:url	https://doi.org/10.1101/012070
resource representing a document's title	The infant airway microbiome in health and disease impacts later asthma development
schema:publication	bioRxiv
resource representing a document's body	covid:c41fdb2efd6d61384a92a84cbba3f8233629a41b#body_text
is schema:about of	named entity 'respiratory illnesses' named entity 'URI' named entity 'microbes' named entity 'cohort' named entity 'accompanying' named entity 'asymptomatic' named entity 'INFANCY' named entity 'RESPIRATORY' named entity 'ALLOIOCOCCUS' named entity 'DOI' named entity 'STRONG' named entity 'ASSOCIATED' named entity 'STREPTOCOCCUS ' named entity 'HAEMOPHILUS' named entity 'DEVELOPMENT' named entity 'TABLE' named entity 'OUR' named entity 'VIRAL AND' named entity 'ILLNESSES' named entity 'EPISODES' named entity 'ASYMPTOMATIC' named entity 'EARLY' named entity 'RESERVOIR' named entity 'CORYNEBACTERIUM' named entity 'STREPTOCOCCUS' named entity 'DISRUPTED' named entity 'RISK' named entity 'USAGE' named entity 'INFECTIONS' named entity 'INFLAMMATORY' named entity 'IMPACTS' named entity 'ASTHMA' named entity 'DATA' named entity 'TRANSIENT' named entity 'LATER' named entity 'INFANT AIRWAY' named entity 'MICROBIOME' named entity 'HEALTH AND DISEASE' named entity 'UPPER' named entity 'INFANTS' named entity 'ANTIBIOTIC' named entity 'VIRUS' named entity 'RESPIRATORY ILLNESS' named entity 'MICROBIOME' named entity 'DETERMINANT' named entity 'SEVERITY' named entity 'AIRWAY INFLAMMATION' named entity '28154' named entity 'ASPIRATES' named entity 'AIRWAYS' named entity 'FUTURE' named entity 'SPREAD' named entity 'MICROBES' named entity 'ASSOCIATED WITH' named entity 'LOWER' named entity 'MORAXELLA' named entity 'ACUTE' named entity 'PREPRINT' named entity 'IS A' named entity 'STAPHYLOCOCCUS ' named entity 'STABLE' named entity 'BACTERIAL COMMUNITY' named entity 'HERE' named entity 'ASTHMA' named entity 'BIRTH COHORT' named entity 'WAS A' named entity 'ACROSS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software