About: Estimating the Risks from COVID-19 Infection in Adult Chemotherapy Patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Estimating the Risks from COVID-19 Infection in Adult Chemotherapy Patients
Creator	Chen, Jiarong Dadhania, Seema Le Calvez, Kerlann Mi, Ella Pakzad-Shahabi, Lillie Williams, Matt
source	MedRxiv
abstract	The SARS-CoV-2 (COVID-19) novel coronavirus represents a significant health risk, particularly in older patients. Cancer is one of the leading causes of death in most rich countries, and delivering chemotherapy may be associated with increased risk in the presence of a pandemic infection. Estimating this risk is crucial in making decisions about balancing risks and benefits from administering chemotherapy. However, there are no specific data about chemotherapy risks per se. Here we develop a simple model to estimate the potential harms in patients undergoing chemotherapy during a COVID outbreak. We use age-related case fatality rates as a basis for estimating risk, and use previous data from risk of death during influenza outbreaks to estimate the additional risk associated with chemotherapy. We use data from randomised trials to estimate benefit across a range of curative and palliative settings, and address the balance of benefit against the risk of harm. We then use those data to estimate the impact on national chemotherapy delivery patterns.
has issue date	2020-03-20(xsd:dateTime)
bibo:doi	10.1101/2020.03.18.20038067
has license	medrxiv
sha1sum (hex)	c41dd9c63d698ec2ec10d82d7f829daff15eeb88
schema:url	https://doi.org/10.1101/2020.03.18.20038067
resource representing a document's title	Estimating the Risks from COVID-19 Infection in Adult Chemotherapy Patients
resource representing a document's body	covid:c41dd9c63d698ec2ec10d82d7f829daff15eeb88#body_text
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