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About:
Self-reported taste and smell disorders in patients with COVID-19: distinct features in China
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Self-reported taste and smell disorders in patients with COVID-19: distinct features in China
Creator
Liu, Yang
Wang, De-Yun
Song, Jia
Liu, Zheng
Liao, Bo
Pan, Li
He, Chao
Ma, Jin
Wang, Hai
Zeng,
Alobid, Isam
Mullol, Joaquim
Wang, Zhi-Chao
Deng, Yi-Ke
Source
MedRxiv
abstract
Objectives: We aimed to explore the frequencies of nasal symptoms in patients with COVID-19, including loss of smell and taste, as well as their presentation as the first symptom of the disease and their association with the severity of COVID-19. Methods: In this retrospective study, 1,206 laboratory-confirmed COVID-19 patients were included and followed-up by telephone call one month after discharged from Tongji Hospital, Wuhan. Demographic data, laboratory values, comorbidities, symptoms, and numerical rating scale scores (0-10) of nasal symptoms were extracted from the hospital medical records, and confirmed or reevaluated by the telephone follow-up. Results: From COVID-19 patients (N = 1,172) completing follow-up, 199 (17%) subjects had severe COVID-19 and 342 (29.2%) reported nasal symptoms. The most common nasal symptom was loss of taste (20.6%, median score = 6), while 11.4% had loss of smell (median score = 5). The incidence of nasal symptom including loss of smell and loss of taste as the first onset symptom was <1% in COVID-19 patients. Loss of smell or taste scores showed no correlation with the scores of other nasal symptoms. Loss of taste scores, but not loss of smell scores, were significantly increased in severe vs. non-severe COVID-19 patients. Interleukin (IL)-6 and lactose dehydrogenase (LDH) serum levels positively correlated with loss of taste scores. About 80% of COVID-19 patients recovered from smell and taste dysfunction in 2 weeks. Conclusion: In the Wuhan COVID-19 cohort, only 1 out of 10 hospital admitted patients had loss of smell while 1 out 5 reported loss of taste which was associated to severity of COVID-19. Most patients recovered smell and taste dysfunctions in 2 weeks.
has issue date
2020-06-15
(
xsd:dateTime
)
bibo:doi
10.1101/2020.06.12.20128298
has license
medrxiv
sha1sum (hex)
c3885d168917da53c27913e71ae643df740289c3
schema:url
https://doi.org/10.1101/2020.06.12.20128298
resource representing a document's title
Self-reported taste and smell disorders in patients with COVID-19: distinct features in China
resource representing a document's body
covid:c3885d168917da53c27913e71ae643df740289c3#body_text
is
schema:about
of
named entity 'China'
named entity 'SEVERITY'
named entity 'PRESENTATION'
named entity 'loss of smell'
named entity 'Self-reported'
named entity 'preprint'
named entity 'loss of sense of smell'
named entity 'olfactory'
named entity 'preprint'
named entity 'upper respiratory tract'
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named entity 'peer review'
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named entity 'medRxiv'
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named entity 'numerical rating scale'
named entity 'symptom'
named entity 'China'
named entity 'medRxiv'
named entity 'taste disorder'
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