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  • Protein microarrays provide a versatile method for the analysis of many protein biochemical activities. Existing DNA microarray analytical methods do not translate to protein microarrays due to differences between the technologies. Here we report a new approach, ProCAT, which corrects for background bias and spatial artifacts, identifies significant signals, filters nonspecific spots, and normalizes the resulting signal to protein abundance. ProCAT provides a powerful and flexible new approach for analyzing many types of protein microarrays.
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  • Creative Commons Attribution-licensed journals
  • BioMed Central academic journals
  • Genetics journals
  • Online-only journals
  • Regional roads in the Republic of Ireland
  • Roads in County Dublin
  • Roads in Dublin (city)
  • Genomics journals
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