About: Chapter 18 Mineral Adjuvants ∗ ∗ The present chapter is an updated version of the chapter “Mineral Adjuvants,” published in Immunopotentiators in Modern Vaccines, p. 217–233. Ed. Virgil Schijns & Derek O'Hagan, Elsevier Science Publishers (2005).

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About: Chapter 18 Mineral Adjuvants ∗ ∗ The present chapter is an updated version of the chapter “Mineral Adjuvants,” published in Immunopotentiators in Modern Vaccines, p. 217–233. Ed. Virgil Schijns & Derek O'Hagan, Elsevier Science Publishers (2005). Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Chapter 18 Mineral Adjuvants ∗ ∗ The present chapter is an updated version of the chapter “Mineral Adjuvants,” published in Immunopotentiators in Modern Vaccines, p. 217–233. Ed. Virgil Schijns & Derek O'Hagan, Elsevier Science Publishers (2005).
Creator	Duroux, L Lindblad, E
source	Elsevier; PMC
abstract	Abstract Mineral adjuvants comprise aluminum hydroxide and phosphate adjuvants as well as calcium phosphate adjuvants. In particular, the aluminum salts have achieved an undisputed status as the most commonly used adjuvants in human and veterinary vaccines. Calcium phosphate adjuvant, later discovered by Edgar Relyveld, constitutes a very interesting alternative and has also been applied both in human and veterinary vaccines. New analytical tools applied in adjuvant research are about to take us to the next level of understanding mineral adjuvants. These tools have been used to characterize mineral adjuvants, but so far, in particular, aluminum-based adjuvants in terms of surface marker expression profiles, isotypic profiles, and cytokine profiles. In the past 10years, the discovery of adjuvant-mediated induction of the NALP3 inflammasome and its impact on the secretion of interleukin (IL)-1β and IL-18 as proinflammatory mediators in the early phases of immune response has been described as an important mechanism for the function of these adjuvants.
has issue date	2017-12-31(xsd:dateTime)
bibo:doi	10.1016/b978-0-12-804019-5.00018-9
has license	els-covid
sha1sum (hex)	c3116b5f9a9a500febbe20c50a770d958fb42188
schema:url	https://doi.org/10.1016/b978-0-12-804019-5.00018-9
resource representing a document's title	Chapter 18 Mineral Adjuvants ∗ ∗ The present chapter is an updated version of the chapter “Mineral Adjuvants,” published in Immunopotentiators in Modern Vaccines, p. 217–233. Ed. Virgil Schijns & Derek O'Hagan, Elsevier Science Publishers (2005).
has PubMed Central identifier	PMC7149584
schema:publication	Immunopotentiators in Modern Vaccines
resource representing a document's body	covid:c3116b5f9a9a500febbe20c50a770d958fb42188#body_text
is schema:about of	named entity 'MINERAL' named entity 'ADJUVANTS' named entity 'kidney' named entity 'proinflammatory cytokines' named entity 'IL-4 receptor' named entity 'equilibrium constant' named entity 'starting material' named entity 'guinea pigs' named entity 'protein' named entity 'free radicals' named entity 'adjuvant' named entity 'Th2' named entity 'IgG1' named entity 'Adsorption' named entity 'aluminum' named entity 'pinocytosis' named entity 'lymph node' named entity 'aluminum' named entity 'vaccine' named entity 'immune response' named entity 'TLRs' named entity 'TLRs' named entity 'adjuvant' named entity 'cutaneous' named entity 'alum' named entity 'monocyte' named entity 'dendritic cell' named entity 'calcium phosphate' named entity 'excretion' named entity 'precipitation' named entity 'immune response' named entity 'adjuvanted' named entity 'MHC' named entity 'aluminum hydroxide' named entity 'local reaction' named entity 'nuclear factor NF-kB' named entity 'medical history' named entity 'Sweden' named entity 'adsorbed' named entity 'spleen' named entity 'adsorptive' named entity 'IL-4' named entity 'thiomersal' named entity 'sedimentation' named entity 'pertussis' named entity 'mineral' named entity 'adjuvants' named entity 'molecule' named entity 'immunization' named entity 'signal transduction' named entity 'degradation products' named entity 'antigen' named entity 'aqueous phase' named entity 'aluminum' named entity 'liver' named entity 'aluminum phosphate' named entity 'anthrax' named entity 'adjuvant' named entity 'aluminum' named entity 'exogenous' named entity 'immunoprecipitation' named entity 'convenience food' named entity 'adsorption' named entity 'adsorbed' named entity 'Th1' named entity 'sensory neurons' named entity 'tetanus' named entity 'formaldehyde' named entity 'adjuvants' named entity 'LPS' named entity 'Th2' named entity 'Th2' named entity 'adsorption' named entity 'immunizing' named entity 'IL-18' named entity 'antigens' named entity 'cryopyrin' named entity 'infectious diseases' named entity 'aluminum' named entity 'flocculation' named entity 'adjuvant' named entity 'pseudorabies'

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