About: Antipsychotic treatment experiences of people with bipolar I disorder: patient perspectives from an online survey

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Antipsychotic treatment experiences of people with bipolar I disorder: patient perspectives from an online survey Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Antipsychotic treatment experiences of people with bipolar I disorder: patient perspectives from an online survey
Creator	Baranwal, Nishtha Bayliss, Martha Bessonova, Leona Carpenter-Conlin, Julia Doane, Michael Rychlec, Kaitlin Sajatovic, Martha Velligan, Dawn Weiden, Peter Yarlas, Aaron O'sullivan, Amy
source	PMC
abstract	BACKGROUND: Oral antipsychotic (AP) medications are frequently prescribed to people with bipolar I disorder (BD-I). A cross-sectional online survey examined the experiences of people living with BD-I with a history of recent AP use. METHODS: Adults with self-reported physician-diagnosed BD-I (N = 200) who received oral APs during the prior year completed a survey on AP-related experiences, including side effects and their perceived burden on social functioning, adherence, and work. Items also assessed preferences for trade-offs (balancing symptom management and side effects) when considering a hypothetical new AP. The perceived impact of specific, prevalent side effects on adherence, work, and preferences for a hypothetical AP were also examined. Analyses were descriptive. RESULTS: The survey sample had a mean age of 43.2 (SD = 12.4) years, was 60% female, and 31% nonwhite. Almost all participants (98%) had experienced AP side effects. Common self-reported side effects were feeling drowsy or tired (83%), lack of emotion (79%), anxiety (79%), dry mouth (76%), and weight gain (76%). Weight gain was cited as the most bothersome side effect, rated by most participants (68%) as “very” or “extremely bothersome.” Nearly half of participants (49%) reported that AP side effects negatively impacted their job performance; almost all (92%) reported that side effects – most commonly anxiety and lack of emotion – negatively impacted social relationships (e.g., family or romantic partners). The most commonly-reported reason for stopping AP use was dislike of side effects (48%). Side effects most likely to lead to stopping or taking less of AP treatment included “feeling like a ‘zombie’” (29%), feeling drowsy or tired (25%), and weight gain (24%). When considering a hypothetical new AP, the most common side effects participants wanted to avoid included AP-induced anxiety (50%), weight gain (48%), and “feeling like a ‘zombie’” (47%). CONCLUSIONS: Side effects of APs were both common and bothersome, and impacted social functioning, adherence, and work. Findings highlight the prevailing unmet need for new APs with more favorable benefit-risk profiles.
has issue date	2020-07-10(xsd:dateTime)
bibo:doi	10.1186/s12888-020-02767-x
bibo:pmid	32631362
has license	cc-by
sha1sum (hex)	c21a44e9411aeeb6f76b1d2d562eff4e9b23e7b1
schema:url	https://doi.org/10.1186/s12888-020-02767-x
resource representing a document's title	Antipsychotic treatment experiences of people with bipolar I disorder: patient perspectives from an online survey
has PubMed Central identifier	PMC7371473
has PubMed identifier	32631362
schema:publication	BMC Psychiatry
resource representing a document's body	covid:c21a44e9411aeeb6f76b1d2d562eff4e9b23e7b1#body_text
is schema:about of	named entity 'Antipsychotic' named entity 'MEDICATIONS' named entity 'bipolar I disorder' named entity 'bipolar I disorder' named entity 'Antipsychotic' named entity 'anticonvulsant drugs' named entity 'Hispanic' named entity 'weight gain' named entity 'weight gain' named entity 'quality of life' named entity 'emotion' named entity 'symptom management' named entity 'self-reported' named entity 'sexual dysfunction' named entity 'dry mouth' named entity 'aripiprazole' named entity 'schizophrenia' named entity 'disease symptoms' named entity 'anxiety' named entity 'symptom' named entity 'weight gain' named entity 'cross-sectional' named entity 'weight gain' named entity 'olanzapine' named entity 'emotion' named entity 'manic episode' named entity 'drug development' named entity 'dyslipidemia' named entity 'romantic relationships' named entity 'weight gain' named entity 'health care professional' named entity 'Antipsychotic' named entity 'sample size' named entity 'job performance' named entity 'general population' named entity 'hypothesis testing' named entity 'weight gain' named entity 'female to male' named entity 'social functioning' named entity 'manic episodes' named entity 'manic episode' named entity 'disability' named entity 'health care' named entity 'interactions with friends' named entity 'social activities' named entity 'clinical practice' named entity 'symptom management' named entity 'Bipolar I disorder' named entity 'social functioning' named entity 'anxiety' named entity 'Standard Deviation' named entity 'dry mouth' named entity 'drug development' named entity 'Symptom' named entity 'weight gain' named entity 'weight gain' named entity 'cross-sectional' named entity 'anxiety' named entity 'manic episodes' named entity 'informed consent' named entity 'Antipsychotic' named entity 'social functioning' named entity 'symptom management' named entity 'sexual dysfunction' named entity 'antidepressants' named entity 'Cary, NC' named entity 'antipsychotics' named entity 'fainting' named entity 'psychiatric disorders' named entity 'weight gain' named entity 'lithium'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software