About: Impact of PCR for respiratory viruses on antibiotic use: Theory and practice

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Impact of PCR for respiratory viruses on antibiotic use: Theory and practice Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Impact of PCR for respiratory viruses on antibiotic use: Theory and practice
Creator	Forster, Johannes Rossen, John Wolfs, Tom Jansen, Nicolaas Van De Pol, Alma Van Loon, Anton Kimpen, Jan Tacke, Carline Uiterwaal, Cuno
Source	Medline; PMC
abstract	RATIONALE FOR THE STUDY: Real‐time polymerase chain reaction (PCR) for respiratory viruses is more sensitive, yet more expensive, than conventionally used direct immunofluorescence (DIF). We determined the impact of real‐time PCR, additional to DIF, on antibiotic prescription in ventilated children with lower respiratory tract infection (LRTI) at admission to the pediatric intensive care unit (PICU). METHODS: First, a multicenter survey study was performed. Subsequently, in a prospective study, children (≤5 years) with LRTI were tested at admission by DIF and PCR. Positive DIF results were reported at the end of the first working day. PICU physicians reported antibiotic treatment on the second working day. After informing them of the PCR result antibiotic treatment was reevaluated. RESULTS: The multicenter survey study (94 respondents) showed that PCR decreased antibiotic use (P < 0.001). In the prospective study 38 children were included, of which 19 (50%) were DIF positive. Of the 19 DIF negative patients 12 (63%) were treated with antibiotics before revealing the PCR result; the PCR test was positive in 9 out of 12. Revealing PCR results did not alter antibiotic treatment. In 7 DIF negative patients antibiotics not given, the PCR test was positive. CONCLUSION: In contrast to their responses to the survey study, in real‐life PICU physicians did not let their antibiotic prescription be influenced by respiratory real‐time PCR in children ventilated for LRTI. Pediatr. Pulmonol. 2011; 46:428–434. © 2010 Wiley‐Liss, Inc.
has issue date	2010-12-30(xsd:dateTime)
bibo:doi	10.1002/ppul.21385
bibo:pmid	21194137
has license	no-cc
sha1sum (hex)	c185afd51440eb8102a60ce7b3858e9a85a24c94
schema:url	https://doi.org/10.1002/ppul.21385
resource representing a document's title	Impact of PCR for respiratory viruses on antibiotic use: Theory and practice
has PubMed Central identifier	PMC7167622
has PubMed identifier	21194137
schema:publication	Pediatr Pulmonol
resource representing a document's body	covid:c185afd51440eb8102a60ce7b3858e9a85a24c94#body_text
is schema:about of	named entity 'PCR' named entity 'respiratory tract' named entity 'survey' named entity 'antibiotic' named entity 'Rationale' named entity 'PCR' named entity 'prospective study' named entity 'result' named entity 'ALTER' named entity 'POSITIVE' named entity 'respondents' named entity 'working day' named entity 'positive' named entity 'test' named entity 'patients' named entity 'expensive' named entity 'antibiotic' named entity 'tested' named entity 'Positive' named entity 'PCR' named entity 'negative' named entity 'Viruses' named entity 'direct immunofluorescence' named entity 'LRTI' named entity 'antibiotic' named entity 'antibiotic' named entity 'antibiotics' named entity 'viruses' named entity 'antibiotic treatment' named entity 'real-time PCR' named entity 'Real-time polymerase chain reaction' named entity 'antibiotic treatment' named entity 'antibiotics' named entity 'Antibiotic' named entity 'Theory and Practice' named entity 'Methods' named entity 'DIF' named entity 'pediatric intensive care unit' named entity 'Mycoplasma pneumoniae' named entity 'antibiotics' named entity 'real-time PCR' named entity 'real-time PCR' named entity 'PICU' named entity 'Patient care' named entity 'PCR' named entity 'PICU' named entity 'antibiotic' named entity 'PICU' named entity 'viruses' named entity 'RSV' named entity 'PICU' named entity 'medical centers' named entity 'asthma exacerbation' named entity 'Foster City' named entity 'LRTI' named entity 'real-time PCR' named entity 'nucleic acid' named entity 'PCR' named entity 'LRTI' named entity 'real-time PCR' named entity 'antibiotics' named entity 'McNemar test' named entity 'bronchiolitis' named entity 'clinician' named entity 'viral infection' named entity 'Basel' named entity 'congenital heart disease' named entity 'real-time PCR' named entity 'PICU' named entity 'LRTI' named entity 'viral testing' named entity 'antibiotic treatment' named entity 'PCR'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software