About: Childhood COVID-19: a multi-center retrospective study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Childhood COVID-19: a multi-center retrospective study
Creator	Wang, Wei Ye, Sheng Shu, Qiang Zhou, Yunlian Xu, Zhen Zhang, Yahua Chen, Zhimin Tong, Lin Wang, Liang, Hong Luo, Yunling Chen, Yinghu Fu, Junfen Hua, Chunzhen Hua1, Chunzhen Luo, Wang Mao, Yueyan Tao, Xiaofen Tong, Chen Wang, Lizhen Wu, Xu Xu, Huiqing Zou, Xiaojie
Source	Elsevier; Medline; PMC
abstract	OBJECTIVES: To investigate the clinical and epidemiological characteristics of pediatric patients with Coronavirus disease-19 (COVID-19). METHODS: Pediatric patients diagnosed with COVID-19 from January 15 to March 15, 2020, from seven hospitals in Zhejiang Province were collected retrospectively and analyzed. RESULTS: Thirty-two children with COVID-19, ranging from 3 months to 18 years old, were enrolled. Family aggregation occurred in 87.5% of infant and preschool-aged children (7/8), and also school-aged children (14/16), but only 12.5% (1/8) of adolescents (p<0. 05, p<0.001). Most of these patients had mild symptoms, mainly fever (20/32), followed by cough (10/32) and fatigue (4/32). The average duration of viral RNA in respiratory samples and gastrointestinal samples were 15.8 d and 28.9 d, respectively. Detox duration in feces decreased with age, namely 39.8 d, 27.5 d and 20.4 d in infant and preschool children, school children and adolescents respectively (p(0-6, -18)<0. 01, p(0-6, -14)<0. 05). Pneumonia was found in 14 children, without any statistical significance in the incidence of pneumonia between different age groups. Thirty patients were treated with antiviral drugs and all patients were stable and gradually improved after admission. CONCLUSIONS: Most children with COVID-19 had a mild process and good prognosis. More attention should be paid to household contact history investigation in the diagnosis of COVID-19 in young children. Viral RNA lasts longer in gastrointestinal system than the respiratory tract, especially in younger children.
has issue date	2020-06-27(xsd:dateTime)
bibo:doi	10.1016/j.cmi.2020.06.015
bibo:pmid	32599159
has license	no-cc
sha1sum (hex)	c11d2e5b93775f45a3659ff42a66a551e9b10e41
schema:url	https://doi.org/10.1016/j.cmi.2020.06.015
resource representing a document's title	Childhood COVID-19: a multi-center retrospective study
has PubMed Central identifier	PMC7319932
has PubMed identifier	32599159
schema:publication	Clin Microbiol Infect
resource representing a document's body	covid:c11d2e5b93775f45a3659ff42a66a551e9b10e41#body_text
is schema:about of	named entity 'Zhejiang Province' named entity 'HOSPITALS' named entity 'MARCH' named entity 'CORONAVIRUS DISEASE' named entity 'METHODS' named entity 'DIAGNOSED WITH COVID-19' named entity 'COVID-19' named entity 'hospitals' named entity 'retrospectively' named entity 'Coronavirus' named entity 'Pediatric patients' named entity 'retrospective study' named entity 'COVID-19' named entity 'clinical symptoms' named entity 'COVID-19' named entity 'gene' named entity 'SARS-CoV-2' named entity 'Demographic data' named entity 'average age' named entity 'Student's t-test' named entity 'emerging infectious disease' named entity 'analysis of variance' named entity 'pairwise comparison' named entity 'pediatric' named entity 'E-mail' named entity 'ANOVA' named entity 'immune systems' named entity 'viral RNA' named entity 'sputum' named entity 'Fisher exact test' named entity 'Coronavirus disease' named entity 'non-parametric' named entity 'IBM SPSS Statistics' named entity '8 days' named entity 'LSD' named entity 'respiratory systems' named entity 'COVID-19' named entity 'Statistical significance' named entity 'Chi-square test' named entity '1, 2' named entity 'retrospective study' named entity 'Coronavirus disease' named entity 'COVID' named entity 'epidemiological' named entity 'pediatric' named entity 'Zhejiang Province' named entity 'COVID-19' named entity 'ZHEJIANG PROVINCE' named entity 'AUTHOR' covid:arg/c11d2e5b93775f45a3659ff42a66a551e9b10e41 named entity 'CENTER' named entity 'CHILDHOOD' named entity 'PRE' named entity 'COVID' named entity 'epidemiological' named entity 'January 15' named entity 'March' named entity 'COVID-19' named entity 'patients'

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