About: Isolation and characterization of a variant porcine epidemic diarrhea virus in China

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Isolation and characterization of a variant porcine epidemic diarrhea virus in China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Isolation and characterization of a variant porcine epidemic diarrhea virus in China
Creator	Bi, Yingzuo Chen, Feng Li, Wei Song, Yanhua Pan, Yongfei Tian, Xiaoyan Wang, Dongdong Zhou, Qingfeng
Source	Medline; PMC
abstract	An outbreak of diarrhea in pigs started in Guangdong, South China in January 2011. Cases were characterized by watery diarrhea, dehydration and vomiting, with 80–100% morbidity and 50–90% mortality in suckling piglets. The causative agent of the diarrhea was ultimately identified as porcine epidemic diarrhea virus (PEDV). In this study, we isolated a PEDV strain designated CHGD-01 from piglet intestines using Vero cell cultures, and its specific cytopathic effects were confirmed in susceptible cells by direct immunofluorescence testing and electron microscopy. The complete genome of CHGD-01 was shown to be 28,035 nucleotides in length, with a similar structure to that of PEDV reference strains. Phylogenetic analyses based on the whole genome revealed that CHGD-01 shared nucleotide sequence identities of 98.2–98.4% with two other Chinese isolates reported in the same year, thus constituting a new cluster. Amino acid sequence analysis based on individual virus genes indicated a close relationship between the spike protein gene of CHGD-01 and the field strain KNU0802 in Korea. Its ORF3 and nucleoprotein genes, however, were divergent from all other sequenced PEDV isolate clusters and therefore formed a new group, suggesting a new variant PEDV isolate in China. Further studies will be required to determine the immunogenicity and pathogenicity of this new variant.
has issue date	2012-09-12(xsd:dateTime)
bibo:doi	10.1186/1743-422x-9-195
bibo:pmid	22967434
has license	cc-by
sha1sum (hex)	c0f05769898b94c3e481a16c7fee9666037bbdab
schema:url	https://doi.org/10.1186/1743-422x-9-195
resource representing a document's title	Isolation and characterization of a variant porcine epidemic diarrhea virus in China
has PubMed Central identifier	PMC3487931
has PubMed identifier	22967434
schema:publication	Virol J
resource representing a document's body	covid:c0f05769898b94c3e481a16c7fee9666037bbdab#body_text
is schema:about of	named entity 'PATHOGENICITY' named entity 'ISOLATES' named entity 'REPORTED' named entity 'ORF3' named entity 'STUDIES' named entity 'MORTALITY' named entity 'COMPLETE' named entity 'CELL CULTURES' named entity 'MORBIDITY' named entity 'NEW' named entity 'PROTEIN GENE' named entity 'KOREA' named entity 'CASES' named entity '100%' named entity 'ITS' named entity 'CYTOPATHIC EFFECTS' named entity 'REQUIRED' named entity 'USING' named entity 'JANUARY' named entity 'shared' named entity 'dehydration' named entity 'effects' named entity 'Isolation' covid:arg/c0f05769898b94c3e481a16c7fee9666037bbdab named entity 'SPECIFIC' named entity 'DEHYDRATION' named entity 'DETERMINE' named entity 'CHINA' named entity 'ISOLATED' named entity 'YEAR' named entity 'CHARACTERIZED' named entity 'LENGTH' named entity 'FIELD' named entity 'IDENTIFIED' named entity 'VOMITING' named entity 'CHINESE' named entity 'INTESTINES' named entity 'SIMILAR' named entity 'TESTING' named entity 'CELLS' named entity 'NUCLEOPROTEIN' named entity 'INDIVIDUAL' named entity '2011' named entity 'IMMUNOGENICITY' named entity 'SOUTH' named entity 'VARIANT' named entity 'CHINA' named entity 'DIARRHEA' named entity 'SPIKE PROTEIN' named entity 'STRAINS' named entity 'VARIANT' named entity 'CLUSTER' named entity 'STARTED' named entity 'DIVERGENT FROM' named entity 'CLOSE RELATIONSHIP' named entity 'CONFIRMED' named entity 'PIGLET' named entity 'STRAIN' named entity 'ELECTRON MICROSCOPY' named entity 'CLUSTERS' named entity 'PIGS' named entity 'OUTBREAK' named entity 'BASED' named entity 'FORMED' named entity 'NUCLEOTIDE SEQUENCE' named entity 'GENOME' named entity 'DESIGNATED' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'ISOLATION' named entity 'CHARACTERIZATION' named entity 'REFERENCE' named entity 'VERO CELL' named entity 'CHGD' named entity 'GENES'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software