About: Monitoring Survivability and Infectivity of Porcine Epidemic Diarrhea Virus (PEDv) in the Infected On-Farm Earthen Manure Storages (EMS)

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About: Monitoring Survivability and Infectivity of Porcine Epidemic Diarrhea Virus (PEDv) in the Infected On-Farm Earthen Manure Storages (EMS) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Monitoring Survivability and Infectivity of Porcine Epidemic Diarrhea Virus (PEDv) in the Infected On-Farm Earthen Manure Storages (EMS)
Creator	Terahara, Kazutaka Cai, Zhangbin Khafipour, Ehsan Adachi, Akio Tun, Hein Young, Natalie
Source	Medline; PMC
abstract	In recent years, porcine epidemic diarrhea virus (PEDv) has caused major epidemics, which has been a burden to North America’s swine industry. Low infectious dose and high viability in the environment are major challenges in eradication of this virus. To further understand the viability of PEDv in the infected manure, we longitudinally monitored survivability and infectivity of PEDv in two open earthen manure storages (EMS; previously referred to as lagoon) from two different infected swine farms identified in the province of Manitoba, Canada. Our study revealed that PEDv could survive up to 9 months in the infected EMS after the initial outbreak in the farm. The viral load varied among different layers of the EMS with an average of 1.1 × 10(5) copies/ml of EMS, independent of EMS temperature and pH. In both studied EMS, the evidence of viral replication was observed through increased viral load in the later weeks of the samplings while there was no new influx of infected manure into the EMS, which was suggestive of presence of potential alternative hosts for PEDv within the EMS. Decreasing infectivity of virus over time irrespective of increased viral load suggested the possibility of PEDv evolution within the EMS and perhaps in the new host that negatively impacted virus infectivity. Viral load in the top layer of the EMS was low and mostly non-infective suggesting that environmental factors, such as UV and sunlight, could diminish the replicability and infectivity of the virus. Thus, frequent agitation of the EMS that could expose virus to UV and sunlight might be a potential strategy for reduction of PEDv load and infectivity in the infected EMS.
has issue date	2016-03-09(xsd:dateTime)
bibo:doi	10.3389/fmicb.2016.00265
bibo:pmid	27014197
has license	cc-by
sha1sum (hex)	c07d89610bf10dbbc4124f1a65ffaab6855954ea
schema:url	https://doi.org/10.3389/fmicb.2016.00265
resource representing a document's title	Monitoring Survivability and Infectivity of Porcine Epidemic Diarrhea Virus (PEDv) in the Infected On-Farm Earthen Manure Storages (EMS)
has PubMed Central identifier	PMC4783413
has PubMed identifier	27014197
schema:publication	Front Microbiol
resource representing a document's body	covid:c07d89610bf10dbbc4124f1a65ffaab6855954ea#body_text
is schema:about of	named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'industry' named entity 'Our' named entity 'sunlight' named entity 'farm' named entity 'Infectivity' named entity 'MANURE' named entity 'MONITORING' named entity 'INITIAL' named entity 'MONTHS' named entity '27S' named entity 'AVERAGE' named entity '1.1' named entity 'EMS' named entity 'UNDERSTAND' named entity 'VIRUS' named entity 'SURVIVE' named entity 'DIFFERENT' named entity 'PROVINCE OF MANITOBA' named entity 'HOSTS' named entity 'FARMS' named entity 'PREVIOUSLY' named entity 'REDUCTION' named entity 'CHALLENGES' named entity 'OBSERVED' named entity 'VIABILITY' named entity 'LOAD' named entity 'ALTERNATIVE' named entity 'VIRUS INFECTIVITY' named entity 'HIGH' named entity 'CAUSED' named entity 'SURVIVABILITY' named entity 'TIME' named entity 'OPEN' named entity 'ERADICATION' named entity 'AGITATION' named entity 'REFERRED TO' named entity 'NORTH AMERICA' named entity 'BURDEN' named entity 'IDENTIFIED' named entity 'PRESENCE OF' named entity 'DIMINISH' named entity 'LAYER' named entity 'INFECTIOUS DOSE' named entity 'LOW' named entity 'LAYERS' named entity 'EVIDENCE OF' named entity 'NON-' named entity 'VIRAL REPLICATION' named entity 'OF PRESENCE' named entity 'MONITORED' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'FREQUENT' named entity 'SURVIVABILITY' named entity 'INFECTED' named entity 'LAGOON' named entity 'FARM' named entity 'INFECTIVITY' named entity 'YEARS' named entity 'LATER' named entity 'POTENTIAL' named entity 'DECREASING' named entity 'WEEKS' named entity 'SUNLIGHT' named entity 'SWINE' named entity 'FARM' named entity 'POSSIBILITY OF' named entity 'SUGGESTIVE OF' named entity 'EPIDEMICS' named entity 'ENVIRONMENT' named entity 'INFECTED' named entity 'OUTBREAK' named entity 'INFECTIVITY' named entity 'TEMPERATURE' named entity 'OUR' named entity 'NEW'

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