About: SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?

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About: SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?
Creator	Egan, Josephine Mazucanti, Caio
Source	Medline; PMC
abstract	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus responsible for the current coronavirus disease 2019 (COVID-19) pandemic, has infected over 3.5 million people all over the world since the first case was reported from Wuhan, China 5 months ago. As more epidemiological data regarding COVID-19 patients is acquired, factors that increase the severity of the infection are being identified and reported. One of the most consistent co-morbidities associated with worse outcome in COVID-19 patients is diabetes, along with age and cardiovascular disease. Studies on the association of diabetes with other acute respiratory infections, namely SARS, MERS, and Influenza, outline what seems to be an underlying factor in diabetic patients that makes them more susceptible to complications. In this review we summarize what we think may be the factors driving this pattern between diabetes, aging and poor outcomes in respiratory infections. We also review therapeutic considerations and strategies for treatment of COVID-19 in diabetic patients, and how the additional challenge of this co-morbidity requires attention to glucose homeostasis so as to achieve the best outcomes possible for patients.
has issue date	2020-06-30(xsd:dateTime)
bibo:doi	10.1186/s12979-020-00192-y
bibo:pmid	32612666
has license	cc-by
sha1sum (hex)	bf1d415b4320016393eed4698be0b1d22a4da91e
schema:url	https://doi.org/10.1186/s12979-020-00192-y
resource representing a document's title	SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?
has PubMed Central identifier	PMC7325192
has PubMed identifier	32612666
schema:publication	Immun Ageing
resource representing a document's body	covid:bf1d415b4320016393eed4698be0b1d22a4da91e#body_text
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