About: Birth seasonality studies in a large Prader

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Birth seasonality studies in a large Prader–Willi syndrome cohort Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Birth seasonality studies in a large Prader–Willi syndrome cohort
Creator	Daniel, \| Butler, Miller, Jennifer Butler, Merlin Correspondence, Merlin Driscoll, J Dykens, \| Gold, June Kimonis, Virginia Tamura, Roy
Source	Medline; PMC
abstract	Prader‐Willi syndrome (PWS) is generally due to sporadic paternal deletions of the chromosome 15q11‐q13 region followed by maternal disomy 15. Advanced maternal age is more commonly seen in those with maternal disomy 15. Environmental factors (e.g., drug use, occupational chemical exposure, infectious agents, and irradiation) could account for chromosome changes. Previous evidence of differences in male and female gametogenesis could suggest an environmental role in the causation of the paternal 15q11‐q13 deletion seen in PWS. Certain occupations such as hydrocarbon‐exposing occupations (e.g., landscaping, farming, and painting) and viral exposure (e.g., human coronavirus 229E causing upper respiratory infections in adults with an incorporation site in the human genome at chromosome 15q11) can be seasonal in nature and contribute to chromosome damage. To assess, we reviewed birth seasonality data in a large cohort of individuals with PWS recruited nationally (N = 355) but no significant differences were seen by month between those with the 15q11‐q13 deletion compared with maternal disomy 15 when analyzing quarterly seasonal patterns. Although early evidence supported birth seasonality differences in PWS, a larger number of individuals in our recent study using advanced genetic testing methods did not find this observation.
has issue date	2019-06-21(xsd:dateTime)
bibo:doi	10.1002/ajmg.a.61263
bibo:pmid	31225937
has license	no-cc
sha1sum (hex)	befec58a6e5ba6b67178801f749ec27cedd646a8
schema:url	https://doi.org/10.1002/ajmg.a.61263
resource representing a document's title	Birth seasonality studies in a large Prader–Willi syndrome cohort
has PubMed Central identifier	PMC7159461
has PubMed identifier	31225937
schema:publication	Am J Med Genet A
resource representing a document's body	covid:befec58a6e5ba6b67178801f749ec27cedd646a8#body_text
is schema:about of	named entity 'study' named entity 'account' named entity 'occupational' named entity 'cohort' named entity 'chromosome' named entity 'evidence' named entity 'female gametogenesis' named entity 'chromosome' named entity 'seasonality' named entity 'occupations' named entity 'damage' named entity 'number' named entity 'seasonality' named entity 'adults' named entity 'disomy' named entity 'advanced' named entity 'PWS' named entity 'methods' named entity 'hydrocarbon' named entity 'upper respiratory infections' named entity 'male and female' named entity 'PWS' named entity 'chromosome' named entity 'Stolwijk' named entity 'nondisjunction' named entity 'Ayabe' named entity 'imprinting' named entity 'hormone' named entity 'virus' named entity 'chromosome 15' named entity 'Stolwijk' named entity 'nondisjunction' named entity 'Environmental factors' named entity 'influenza viruses' named entity 'chromosomes' named entity 'advanced maternal age' named entity 'gametogenesis' named entity 'DNA replication' named entity 'genetic testing' named entity 'deletions' named entity 'microvasculature' named entity 'chromosome' named entity 'imprinting' named entity 'DNA replication' named entity 'nondisjunction' named entity 'hydrocarbon' named entity 'human coronavirus' named entity 'hormonal imbalance' named entity 'Japan' named entity 'disomy' named entity 'equal in distribution' named entity 'human reproduction' named entity 'chemical exposure' named entity 'chromosome' named entity 'Environmental factors' named entity 'disomy' named entity 'PWS' named entity 'Prader-Willi syndrome' named entity 'meiosis' named entity 'disomy' named entity 'statistical significance' named entity 'ovulation' named entity 'general population' named entity 'inversions' named entity 'disomy' named entity 'Mascarello' named entity 'meiosis' named entity 'fetal life' named entity 'hypothalamus' named entity 'Korea' named entity 'translocations' named entity 'male and female'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software