About: MERS-coronavirus: From discovery to intervention

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	MERS-coronavirus: From discovery to intervention
Creator	Haagmans, Bart Okba, Nisreen Raj, V Widagdo, W
source	Elsevier; Medline; PMC
abstract	Middle East respiratory syndrome coronavirus (MERS-CoV) still causes outbreaks despite public awareness and implementation of health care measures, such as rapid viral diagnosis and patient quarantine. Here we describe the current epidemiological picture of MERS-CoV, focusing on humans and animals affected by this virus and propose specific intervention strategies that would be appropriate to control MERS-CoV. One-third of MERS-CoV patients develop severe lower respiratory tract infection and succumb to a fatal outcome; these patients would require effective therapeutic antiviral therapy. Because of the lack of such intervention strategies, supportive care is the best that can be offered at the moment. Limiting viral spread from symptomatic human cases to health care workers and family members, on the other hand, could be achieved through prophylactic administration of MERS-CoV neutralizing antibodies and vaccines. To ultimately prevent spread of the virus into the human population, however, vaccination of dromedary camels – currently the only confirmed animal host for MERS-CoV – may be the best option to achieve a sustained drop in human MERS cases in time. In the end, a One Health approach combining all these different efforts is needed to tackle this zoonotic outbreak.
has issue date	2016-12-23(xsd:dateTime)
bibo:doi	10.1016/j.onehlt.2016.12.001
bibo:pmid	28616497
has license	cc-by-nc-nd
sha1sum (hex)	beb38f99a59fa3129e34eadfc28c9d46438ec820
schema:url	https://doi.org/10.1016/j.onehlt.2016.12.001
resource representing a document's title	MERS-coronavirus: From discovery to intervention
has PubMed Central identifier	PMC5454172
has PubMed identifier	28616497
schema:publication	One Health
resource representing a document's body	covid:beb38f99a59fa3129e34eadfc28c9d46438ec820#body_text
is schema:about of	named entity 'VIRUS' named entity 'PATIENTS' named entity 'PATIENT' named entity 'OUTBREAK' named entity 'SUPPORTIVE CARE' named entity 'FAMILY MEMBERS' named entity 'SPREAD' named entity 'ANIMALS' named entity 'COMBINING' named entity 'DROP' named entity 'LIMITING' named entity 'PICTURE' named entity 'DROMEDARY' named entity 'MERS' named entity 'HERE' named entity 'CONFIRMED' named entity 'APPROACH' named entity 'EPIDEMIOLOGICAL' named entity 'PREVENT' named entity 'VIRAL' named entity 'epidemiological' named entity 'effective' named entity 'viral' named entity 'awareness' named entity 'zoonotic' named entity 'fatal' named entity 'http' named entity 'IMPLEMENTATION' named entity 'BEST' named entity 'INTERVENTION' named entity 'OFFERED' named entity 'CASES' named entity 'CAUSES' named entity 'SUSTAINED' named entity 'INTERVENTION STRATEGIES' named entity 'FATAL OUTCOME' named entity 'MEASURES' named entity 'HUMANS' named entity 'END' named entity 'OPTION' named entity 'ANTIVIRAL THERAPY' named entity 'THERAPEUTIC' named entity 'NC-' named entity 'CORONAVIRUS' named entity 'LICENSE' named entity 'DISCOVERY' named entity 'ORG' named entity 'MERS' named entity 'PUBLIC' named entity 'DIFFERENT' named entity 'HAND' named entity 'CURRENT' named entity 'ADMINISTRATION' named entity 'APPROPRIATE' named entity 'SPECIFIC' named entity 'RAPID' named entity 'THESE' named entity 'DIAGNOSIS' named entity 'EFFECTIVE' named entity 'LOWER RESPIRATORY TRACT INFECTION' named entity 'HUMAN' named entity 'OUTBREAKS' named entity 'SYMPTOMATIC' named entity 'SEVERE' named entity 'AWARENESS' named entity 'TIME' named entity 'VACCINATION' named entity 'LACK' named entity 'COULD BE' named entity 'WORKERS' named entity 'NEEDED' named entity 'FOCUSING' named entity 'ONE HEALTH' named entity 'HUMAN POPULATION' named entity 'MOMENT' named entity 'VACCINES' named entity 'AFFECTED' named entity 'PROPHYLACTIC'

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