About: Effects of Triton X-100 on Properties of Hemoglobin and Controlled Release of Drug in Hemoglobin/Ribavirin/H2O System

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About: Effects of Triton X-100 on Properties of Hemoglobin and Controlled Release of Drug in Hemoglobin/Ribavirin/H2O System Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of Triton X-100 on Properties of Hemoglobin and Controlled Release of Drug in Hemoglobin/Ribavirin/H2O System
Creator	Physico-Chimica, Acta Sinica,
Source	Elsevier; PMC
abstract	Abstract Effects of Triton X-100 on the properties of hemoglobin (Hb) and on the controlled release of ribavirin were studied using the methods of UV-Vis spectrum, fluorescence spectrum, zeta potential, conductivity, high-performance liquid chromatographic (HPLC), and image morphology in Hb/ribavirin/H2O system. With the increase of concentration of Triton X-100 in the system, the intrinsic fluorescence intensity, synchronous fluorescence intensity, fluorescence polarization, zeta potential, and morphology of Hb all changed gradually, and the ribavirin located on the Hb surface was dissociated and released out. When the concentration of Triton X-100 was higher than 1×10−5 mol·L−1, the stronger interaction of Triton X-100 with Hb was predominant. Hb was unfolded and denaturized. A little Triton X-100 can protect Hb from the effects of ribavirin.
has issue date	2008-04-30(xsd:dateTime)
bibo:doi	10.1016/s1872-1508(08)60029-7
has license	els-covid
sha1sum (hex)	be4dc027916ccb353a04375ddebeb2d836ca74f5
schema:url	https://doi.org/10.1016/s1872-1508%2808%2960029-7
resource representing a document's title	Effects of Triton X-100 on Properties of Hemoglobin and Controlled Release of Drug in Hemoglobin/Ribavirin/H2O System
has PubMed Central identifier	PMC7148898
schema:publication	Acta Physico-Chimica Sinica
resource representing a document's body	covid:be4dc027916ccb353a04375ddebeb2d836ca74f5#body_text
is schema:about of	named entity 'TRITON X-100' named entity 'PROPERTIES' named entity 'surface' named entity 'intensity' named entity 'interaction' named entity 'located' named entity 'image' named entity 'Properties' named entity 'FLUORESCENCE POLARIZATION' named entity 'CONDUCTIVITY' named entity 'CHANGED' named entity 'RIBAVIRIN' named entity 'TRITON X-100' named entity 'HEMOGLOBIN' named entity 'FLUORESCENCE INTENSITY' named entity 'INTERACTION' named entity 'CONTROLLED RELEASE' named entity 'METHODS' named entity 'EFFECTS' named entity 'EFFECTS' named entity 'HEMOGLOBIN' named entity 'PREDOMINANT' named entity 'USING' named entity 'IMAGE' named entity 'PROPERTIES' named entity '921' named entity 'DISSOCIATED' named entity 'UV-VIS SPECTRUM' named entity 'RELEASED' named entity 'CONTROLLED RELEASE' named entity 'SYNCHRONOUS' named entity 'LIQUID' named entity 'DRUG' named entity 'SYSTEM' named entity 'HIGH' named entity 'SYSTEM' named entity 'PERFORMANCE' named entity 'INCREASE' named entity 'SURFACE' named entity 'CONCENTRATION OF' named entity 'MOL' named entity 'INTRINSIC' named entity 'ZETA POTENTIAL' named entity '925' named entity 'FLUORESCENCE SPECTRUM' named entity '2 O' named entity 'MORPHOLOGY' named entity '9710' covid:arg/be4dc027916ccb353a04375ddebeb2d836ca74f5 named entity 'UV-Vis' named entity 'Effects' named entity 'zeta potential' named entity 'mol' named entity 'spectrum' named entity 'Drug' named entity 'fluorescence polarization' named entity 'ribavirin' named entity 'fluorescence intensity' named entity 'Triton X-100' named entity 'morphology' named entity 'Triton X-100' named entity 'ribavirin' named entity 'controlled release' named entity 'fluorescence spectrum' named entity 'Hemoglobin' named entity 'Controlled Release' named entity 'Ribavirin' named entity 'system' named entity 'Ribavirin' named entity 'Triton X-100' named entity 'tyrosine' named entity 'ribavirin' named entity 'electric field' named entity 'equilibrium' named entity 'dielectric constant' named entity 'zeta potential' named entity 'morphology' named entity 'hydrogen bonding' named entity 'oxygen' named entity 'hydrophilic' named entity 'ribavirin' named entity 'Triton X-100'

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