About: Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves

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About: Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves
Creator	De Mia, Gian Gobbi, Paola Iscaro, Carmen Pellegrini, Claudia Petrini, Stefano Righi, Cecilia Rossi, Elisabetta Scoccia, Eleonora Viola, Giulio
Source	Medline; PMC
abstract	Different types of vaccines against Infectious Bovine Rhinotracheitis (IBR) are commercially available. Among these, inactivated glycoprotein E (gE)-deleted marker vaccines are commonly used, but their ability to induce passive immunity is poorly known. Here, we evaluated the passive immunity transferred from dams immunised with commercial inactivated gE-deleted marker vaccines to calves. We vaccinated 12 pregnant cattle devoid of neutralising antibodies against Bovine alphaherpesvirus 1 (BoHV-1) and divided them into two groups with 6 animals each. Both groups were injected with a different inactivated gE-deleted marker vaccine administrated via intranasal or intramuscular routes. An additional 6 pregnant cattle served as the unvaccinated control group. After calving, the number of animals in each group was increased by the newborn calves. In the dams, the humoral immune response was evaluated before calving and, subsequently, at different times until post-calving day 180 (PCD180). In addition, the antibodies in colostrum, milk, and in serum samples from newborn calves were evaluated at different times until PCD180. The results indicated that inactivated glycoprotein E (gE)-deleted marker vaccines are safe and produce a good humoral immune response in pregnant cattle until calving and PCD180. Moreover, results showed that, in calf serum, passive immunity persists until PCD180.
has issue date	2020-01-04(xsd:dateTime)
bibo:doi	10.3390/vaccines8010014
bibo:pmid	31947899
has license	cc-by
sha1sum (hex)	bbca7e2fd355a861e69edaaeadddf2754e276c0e
schema:url	https://doi.org/10.3390/vaccines8010014
resource representing a document's title	Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves
has PubMed Central identifier	PMC7157740
has PubMed identifier	31947899
schema:publication	Vaccines (Basel)
resource representing a document's body	covid:bbca7e2fd355a861e69edaaeadddf2754e276c0e#body_text
is schema:about of	named entity 'glycoprotein' named entity 'administrated' named entity 'Immunity' named entity 'INTRANASAL' named entity 'COMMERCIAL' named entity 'MARKER VACCINES' covid:arg/bbca7e2fd355a861e69edaaeadddf2754e276c0e named entity 'antibodies' named entity 'serum' named entity 'produce' named entity 'times' named entity 'intramuscular' named entity 'passive immunity' named entity 'newborn calves' named entity 'colostrum' named entity 'intranasal' named entity 'passive immunity' named entity 'marker vaccine' named entity 'passive immunity' named entity 'antibodies' named entity 'IBR' named entity 'humoral immune response' named entity 'serum samples' named entity 'colostrum' named entity 'Switzerland' named entity 'virulent' named entity 'serum' named entity 'seronegative' named entity 'vaginitis' named entity 'colostrum' named entity 'passive immunity' named entity 'serum samples' named entity 'infection' named entity 'Bovine alphaherpesvirus 5' named entity 'Staphylococcus spp' named entity 'vaccine' named entity 'colostrum' named entity 'Marker vaccines' named entity 'antibody' named entity 'vaccination' named entity 'vaccination' named entity 'vaccine' named entity 'saponin' named entity 'Norway' named entity 'Vaccine' named entity 'clinical signs' named entity 'intramuscularly' named entity 'passive immunity' named entity 'serological' named entity 'colostrum' named entity 'Bovine Viral Diarrhea Virus' named entity 'vaccine' named entity 'vaccination' named entity 'vacutainer' named entity 'clinical signs' named entity 'P-value' named entity 'vaccination' named entity 'serum' named entity 'passive immunity' named entity 'cattle' named entity 'virus' named entity 'pregnancy' named entity 'infection' named entity 'serum samples' named entity 'intramuscularly' named entity 'ceftiofur' named entity 'intranasally' named entity 'pregnant females' named entity 'modified-live' named entity 'passive immunity' named entity 'C.R.' named entity 'cellular immunity' named entity 'vaccine'

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