About: LifeGene—a large prospective population-based study of global relevance

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About: LifeGene—a large prospective population-based study of global relevance Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	LifeGene—a large prospective population-based study of global relevance
Creator	Maeurer, Markus Pedersen, N Adami, Hans-Olov Almqvist, Catarina Franks, Paul Groop, Leif Ingelsson, Erik Kere, Juha Lissner, Lauren Litton, Jan-Eric Michaëlsson, Karl Palmgren, Juni Pedersen, Nancy Pershagen, Göran Ploner, Alexander Tybring, Gunnel Adami, H.-O Almqvist, C Franks, P Groop, L Ingelsson, Á Litton, J.-E Maeurer, M Michaëlsson, K Palmgren, Á Patrick, • Pershagen, G Ploner, Á Sullivan, F Sullivan, P Tybring, Á
Source	Medline; PMC
abstract	Studying gene-environment interactions requires that the amount and quality of the lifestyle data is comparable to what is available for the corresponding genomic data. Sweden has several crucial prerequisites for comprehensive longitudinal biomedical research, such as the personal identity number, the universally available national health care system, continuously updated population and health registries and a scientifically motivated population. LifeGene builds on these strengths to bridge the gap between basic research and clinical applications with particular attention to populations, through a unique design in a research-friendly setting. LifeGene is designed both as a prospective cohort study and an infrastructure with repeated contacts of study participants approximately every 5 years. Index persons aged 18–45 years old will be recruited and invited to include their household members (partner and any children). A comprehensive questionnaire addressing cutting-edge research questions will be administered through the web with short follow-ups annually. Biosamples and physical measurements will also be collected at baseline, and re-administered every 5 years thereafter. Event-based sampling will be a key feature of LifeGene. The household-based design will give the opportunity to involve young couples prior to and during pregnancy, allowing for the first study of children born into cohort with complete pre-and perinatal data from both the mother and father. Questions and sampling schemes will be tailored to the participants’ age and life events. The target of LifeGene is to enrol 500,000 Swedes and follow them longitudinally for at least 20 years.
has issue date	2010-11-21(xsd:dateTime)
bibo:doi	10.1007/s10654-010-9521-x
bibo:pmid	21104112
has license	no-cc
sha1sum (hex)	bbc3fde6f1714f16d78a8d45e1443f476294f04b
schema:url	https://doi.org/10.1007/s10654-010-9521-x
resource representing a document's title	LifeGene—a large prospective population-based study of global relevance
has PubMed Central identifier	PMC7087900
has PubMed identifier	21104112
schema:publication	Eur J Epidemiol
resource representing a document's body	covid:bbc3fde6f1714f16d78a8d45e1443f476294f04b#body_text
is schema:about of	named entity 'genomic' named entity 'PROSPECTIVE' named entity 'APPLICATIONS' named entity 'THESE' named entity 'INFRASTRUCTURE' named entity 'STRENGTHS' named entity 'REPEATED' named entity 'NUMBER' named entity 'GLOBAL' named entity 'CLINICAL' named entity 'GENE-ENVIRONMENT INTERACTIONS' named entity 'BASIC RESEARCH' named entity 'AVAILABLE' named entity 'PREREQUISITES' named entity 'PERSONAL IDENTITY' named entity 'DESIGN' named entity 'SWEDEN' named entity 'REGISTRIES' named entity 'THE GAP' named entity 'QUALITY' named entity 'DATA' named entity 'WHAT' named entity 'BIOMEDICAL RESEARCH' named entity 'STUDY' named entity 'PARTICULAR' named entity 'CONTACTS' named entity 'GENOMIC DATA' named entity 'UNIQUE' named entity 'COMPREHENSIVE' named entity 'HEALTH CARE SYSTEM' named entity 'BRIDGE' named entity 'PARTICIPANTS' named entity 'LIFESTYLE' named entity 'HEALTH' named entity 'NATIONAL' named entity 'LONGITUDINAL' named entity 'SETTING' named entity 'POPULATION' named entity 'UPDATED' named entity 'ATTENTION' named entity 'PROSPECTIVE COHORT STUDY' named entity 'FRIENDLY' named entity 'RESEARCH' named entity 'LARGE' named entity 'RELEVANCE' named entity 'POPULATION-BASED STUDY' named entity 'study' named entity 'personal identity number' named entity 'participants' named entity 'health' named entity 'basic'

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