About: Renal outcomes of neonates with early presentation of posterior urethral valves: a 10-year single center experience

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About: Renal outcomes of neonates with early presentation of posterior urethral valves: a 10-year single center experience Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Renal outcomes of neonates with early presentation of posterior urethral valves: a 10-year single center experience
Creator	Pagni, Sarah Coquillette, Madeline Cataltepe, Sule Lee, Richard Stein, Deborah
source	PMC
abstract	OBJECTIVE: Evaluate renal outcomes and early predictive factors in infants with congenital posterior urethral valves who required catheter or surgical urinary tract decompression within the first 7 days of life. STUDY DESIGN: A 10-year retrospective study at a single hospital. Primary outcomes were estimated glomerular filtration rate (eGFR) and development of end stage renal disease (ESRD). RESULTS: Of 35 infants, 50% developed eGFR <90 mL/min/1.73 m(2) and 15% progressed to ESRD. Nadir creatinine, need for invasive ventilation in the newborn period, and need for surgical diversion after catheter diversion were associated with worse outcomes. 50% of infants requiring invasive ventilation as neonates developed eGFR <60 mL/min/1.73 m(2) in childhood. CONCLUSIONS: Half of infants with early presentation and intervention developed significant renal insufficiency in childhood, similar to children with later presentation or who had fetal intervention. Invasive ventilation in the newborn period and need for surgical urinary diversion are associated with worse outcomes.
has issue date	2019-08-30(xsd:dateTime)
bibo:doi	10.1038/s41372-019-0489-4
bibo:pmid	31471579
has license	no-cc
sha1sum (hex)	bbb394c3f595daa350f57d9fddc2246326bcea9a
schema:url	https://doi.org/10.1038/s41372-019-0489-4
resource representing a document's title	Renal outcomes of neonates with early presentation of posterior urethral valves: a 10-year single center experience
has PubMed Central identifier	PMC7223871
has PubMed identifier	31471579
schema:publication	J Perinatol
resource representing a document's body	covid:bbb394c3f595daa350f57d9fddc2246326bcea9a#body_text
is schema:about of	named entity 'min' named entity 'renal disease' named entity 'STUDY DESIGN' named entity 'CONGENITAL POSTERIOR URETHRAL VALVES' named entity 'PRIMARY' named entity 'END STAGE RENAL DISEASE' named entity 'NEONATES' named entity 'ESTIMATED GLOMERULAR FILTRATION RATE' named entity 'RESULTS' named entity 'RETROSPECTIVE STUDY' named entity 'OBJECTIVE' named entity 'CATHETER' named entity 'developed' named entity 'infants' named entity 'life' named entity 'renal' named entity 'ventilation' named entity 'eGFR' named entity 'eGFR' named entity 'ESRD' named entity 'catheter' named entity 'estimated glomerular filtration rate' named entity 'end stage renal disease' named entity 'ESRD' named entity 'congenital' named entity 'premature infants' named entity 'neonatal period' named entity 'catheter' named entity 'Mann-Whitney U test' named entity 'LUTO' named entity 'follow-up' named entity 'follow-up' named entity 'gestational age' named entity 'Fetal intervention' named entity 'invasive ventilation' named entity 'CKD' named entity 'fetal' named entity 'perinatal' named entity 'surgical complications' named entity 'postnatal' named entity 'PUV' named entity 'vesicoureteral reflux' named entity 'LUTO' named entity 'sample size' named entity 'ESRD' named entity 'Kruskal-Wallis test' named entity 'electronic data capture' named entity 'SPSS' named entity 'prematurity' named entity 'Boston Children's Hospital' named entity 'dialysis' named entity 'invasive ventilation' named entity 'urinary tract' named entity 'LUTO' named entity 'short duration' named entity 'neonatal intensive care' named entity 'eGFR' named entity 'hydroureter' named entity 'lower urinary tract obstruction' named entity 'ESRD' named entity 'creatinine' named entity 'follow-up' named entity 'Kruskal-Wallis test' named entity 'ablation' named entity 'urologic' named entity 'urinary diversion' named entity 'pulmonary hypoplasia' named entity 'ESRD' named entity 'creatinine' named entity 'follow-up' named entity 'gestation' named entity 'prognosis' named entity 'oligohydramnios' named entity 'Bonferroni correction' named entity 'eGFR' named entity 'urologic' named entity 'eGFR'

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