About: Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study()

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study() Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study()
Creator	Prata-Barbosa, Arnaldo Colleti, José Santos, Santos, Dos Clara De Magalhães-Barbosa, Maria José, Antonio Paula, Ana Raymundo, Carlos Torre, La Almeida De Azevedo, Zina Almeida, Natália Andrea, Flavia Augusta, Augusta, Elaine Bellinat, Novaes Bellinat, Vivian Brandão, Igor Camera Gregory, Simone Camera, Simone Carla De Souza, Daniela Carla De Souza, Carlos Castro, Rodriguez Ciuffo, Fernanda Ciuffo, Monte Coelho Fonseca Da Mota, Isabele Colleti, Ana Cunha, Ledo Da Costa, Monte Da Costa, Peixoto De Castro, Vieira De Lima, Peixoto De Oliveira, Caino De Oliveira, Lucio De Seixas Zeitel, Raquel De, Seixas Esteves Vieira De Castro, Daniela Esteves, Roberta Fabíola, Peixoto Ferreira, Fabíola Ferreira, La Figueiredo, Neves Flavio Peixoto De Lima, Cristian Flavio, Lucio Foronda, Krepel Genu, Santos Hilário, Daniel Lanziotti, Vanessa Lima-Setta, Fernanda Lorenzo, Raquel Lorenzo, Vivian Novais De Carvalho, Rosana Oliveira Boedo, Fernanda Paula, Novaes Peres Da Silva, Thiago Pulcheri, Fernanda Pulcheri, Lucas Raymundo, Felipe Rezende, Caino Rezende, Felipe Riveiro, Paula Rodrigues, Gustavo Santos, Vanessa Silva, Arnaldo Soares Lanziotti, Vanessa Soares Lanziotti, Roberta Tonial, Cristian Tonial, José Torre, Torre, Elaine Vieira De Castro, Roberta Zeitel, Lucas
Source	Elsevier; Medline; PMC
abstract	OBJECTIVE: To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19. METHOD: Prospective, multicenter, observational study, in 19 pediatric intensive care units. Patients aged 1 month to 19 years admitted consecutively (March–May 2020) were included. Demographic, clinical-epidemiological features, treatment, and outcomes were collected. Subgroups were compared according to comorbidities, age < 1 year, and need for invasive mechanical ventilation. A multivariable logistic regression model was used for predictors of severity. RESULTS: Seventy-nine patients were included (ten with multisystemic inflammatory syndrome). Median age 4 years; 54% male (multisystemic inflammatory syndrome, 80%); 41% had comorbidities (multisystemic inflammatory syndrome, 20%). Fever (76%), cough (51%), and tachypnea (50%) were common in both groups. Severe symptoms, gastrointestinal symptoms, and higher inflammatory markers were more frequent in multisystemic inflammatory syndrome. Interstitial lung infiltrates were common in both groups, but pleural effusion was more prevalent in the multisystemic inflammatory syndrome group (43% vs. 14%). Invasive mechanical ventilation was used in 18% (median 7.5 days); antibiotics, oseltamivir, and corticosteroids were used in 76%, 43%, and 23%, respectively, but not hydroxychloroquine. The median pediatric intensive care unit length-of-stay was five days; there were two deaths (3%) in the non- multisystemic inflammatory syndrome group. Patients with comorbidities were older, and comorbidities were independently associated with the need for invasive mechanical ventilation (OR 5.5; 95% CI, 1.43–21.12; p = 0.01). CONCLUSIONS: In Brazilian pediatric intensive care units, COVID-19 had low mortality, age less than 1 year was not associated with a worse prognosis, and patients with multisystemic inflammatory syndrome had more severe symptoms, higher inflammatory biomarkers, and a greater predominance of males, but only comorbidities and chronic diseases were independent predictors of severity.
has issue date	2020-08-04(xsd:dateTime)
bibo:doi	10.1016/j.jped.2020.07.002
bibo:pmid	32781034
has license	no-cc
sha1sum (hex)	bafe70e94c28349fd06fd3f6cec430210b6e06bf
schema:url	https://doi.org/10.1016/j.jped.2020.07.002
resource representing a document's title	Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study()
has PubMed Central identifier	PMC7402103
has PubMed identifier	32781034
schema:publication	J Pediatr (Rio J)
resource representing a document's body	covid:bafe70e94c28349fd06fd3f6cec430210b6e06bf#body_text
is schema:about of	named entity 'COVID-19' named entity 'prospective' named entity 'COVID-19' named entity 'intensive care' named entity 'COVID-19' named entity 'comorbidities' named entity 'MIS-C' named entity 'coronavirus' named entity 'tachypnea' named entity 'MIS' named entity 'interleukin-6'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software