About: ISOLATION AND CHARACTERIZATION OF AN EXOPOLYMER PRODUCED BY BACILLUS LICHENIFORMIS: IN VITRO ANTIVIRAL ACTIVITY AGAINST ENVELOPED VIRUSES

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About: ISOLATION AND CHARACTERIZATION OF AN EXOPOLYMER PRODUCED BY BACILLUS LICHENIFORMIS: IN VITRO ANTIVIRAL ACTIVITY AGAINST ENVELOPED VIRUSES Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	ISOLATION AND CHARACTERIZATION OF AN EXOPOLYMER PRODUCED BY BACILLUS LICHENIFORMIS: IN VITRO ANTIVIRAL ACTIVITY AGAINST ENVELOPED VIRUSES
Creator	Abrusci, C Bello-Morales, R Gironès, N Jiménez-Barbero, J López-Guerrero, J Poveda, A Sánchez-León, E
Source	Elsevier; PMC
abstract	The exopolymer (EPSp) produced by the strain B. licheniformis IDN-EC was isolated and characterized using different techniques (MALDI-TOF, NMR, ATR-FTIR, TGA, DSC, SEM). The results showed that the low molecular weight EPSp contained a long polyglutamic acid and an extracellular teichoic acid polysaccharide. The latter was composed of poly(glycerol phosphate) and was substituted at the 2-position of the glycerol residues with a αGal and αGlcNH(2). The αGal O-6 position was also found to be substituted by a phosphate group. The antiviral capability of this EPSp was also tested on both enveloped (herpesviruses HSV, PRV and vesicular stomatitis VSV) and non-enveloped (MVM) viruses. The EPSp was efficient at inhibiting viral entry for the herpesviruses and VSV but was not effective against non-enveloped viruses. The in vivo assay of the EPSp in mice showed no signs of toxicity which could allow for its application in the healthcare sector.
has issue date	2020-07-08(xsd:dateTime)
bibo:doi	10.1016/j.carbpol.2020.116737
has license	no-cc
sha1sum (hex)	b9ff2c5643a691578f7f711810230fc4e10351be
schema:url	https://doi.org/10.1016/j.carbpol.2020.116737
resource representing a document's title	ISOLATION AND CHARACTERIZATION OF AN EXOPOLYMER PRODUCED BY BACILLUS LICHENIFORMIS: IN VITRO ANTIVIRAL ACTIVITY AGAINST ENVELOPED VIRUSES
has PubMed Central identifier	PMC7345415
schema:publication	Carbohydr Polym
resource representing a document's body	covid:b9ff2c5643a691578f7f711810230fc4e10351be#body_text
is schema:about of	named entity 'potential' named entity 'Highlights' named entity 'produced' named entity 'EPSp' named entity 'electrostatic' named entity 'B. licheniformis' named entity 'EPSp' named entity 'negative' named entity 'EPSp' named entity 'EPSp' named entity 'beta-galactosidase' named entity 'Bruker' named entity 'EPSp' named entity 'antibody' named entity 'exopolymer' named entity 'methanol' named entity 'PRV' named entity 'nitrogen' named entity 'biodegradation' named entity 'EPSp' named entity 'PBS' named entity '50% tissue culture infective dose' named entity 'KDa' named entity 'polymer' named entity 'antibodies' named entity 'coronavirus pandemic' named entity 'biodegradation' named entity 'Germany' named entity 'pharmaceutical industry' named entity 'alanine aminotransferase' named entity 'HSQC' named entity 'EPSp' named entity 'EPSp' named entity 'pandemics' named entity 'predation' named entity 'EPSp' named entity 'enveloped viruses' named entity 'FeSO4' named entity 'VSV' named entity 'EPS' named entity 'centrifugation' named entity 'virus' named entity 'viral infection' named entity 'carbon source' named entity 'kDa' named entity 'EPSp' named entity 'biodegradation' named entity 'EPSp' named entity 'weight gain' named entity 'EPSp' named entity 'antiviral' named entity 'endocytosis' named entity 'RPMI' named entity 'phosphate groups' named entity 'viral infection' named entity 'EPS' named entity 'urea' named entity 'biodegradation' named entity 'proton' named entity 'amide group' named entity 'enveloped viruses' named entity 'extracellular' named entity 'MGM' named entity 'bioreactor' named entity 'NaCl' named entity 'SARS-CoV-2' named entity 'polar bonds' named entity 'galactose' named entity 'microplate reader' named entity 'bilirubin' named entity 'Stintzing' named entity 'biochemical analysis' named entity 'diffusion' named entity 'thrice' named entity 'Attenuated Total Reflectance' named entity 'paraformaldehyde' named entity 'EPS'

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