About: Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties
Creator	Balzarini, J Cascante, M De Clerq, E Font-Bardia, M Piulats, J Pujol, Romero, M Rosell, E Zanuy, M
Source	Elsevier; Medline; PMC
abstract	Abstract The aqueous extraction of the sesquiterpene lactone xanthatin from Xanthium spinosum L. favours the conversion of xanthinin (1) to xanthatin (2) via the loss of acetic acid. The cytotoxic (Hep-G2 and L1210 human cell lines) and antiviral activities of isolated xanthatin are established. This natural compound shows significant cytotoxicity against the Hep-G2 cell line and our experimental results reveal its strong anti-angiogenesis capacity in vitro. The structure of xanthatin is determined by spectroscopic methods and for the first time confirmed by X-ray diffraction.
has issue date	2015-01-27(xsd:dateTime)
bibo:doi	10.1016/j.ejmech.2014.11.060
bibo:pmid	25481815
has license	els-covid
sha1sum (hex)	b95dae179ce90376b0367517e1521a16186653a7
schema:url	https://doi.org/10.1016/j.ejmech.2014.11.060
resource representing a document's title	Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties
has PubMed Central identifier	PMC7115430
has PubMed identifier	25481815
schema:publication	European Journal of Medicinal Chemistry
resource representing a document's body	covid:b95dae179ce90376b0367517e1521a16186653a7#body_text
is schema:about of	named entity 'natural compound' named entity 'reveal' named entity 'extraction' named entity 'X-RAY DIFFRACTION' named entity 'SIGNIFICANT' named entity 'ISOLATED' named entity 'STRONG' named entity 'EXPERIMENTAL RESULTS' named entity 'L1210' named entity 'ANTI-ANGIOGENESIS' named entity 'NATURAL COMPOUND' named entity 'STRUCTURE' named entity 'CYTOTOXIC' named entity 'EXTRACTION' named entity 'METHODS' named entity 'OPTIMIZATION' named entity 'ANTIVIRAL' named entity 'HEP-G2 CELL' named entity 'ACETIC ACID' named entity 'PROPERTIES' named entity 'XANTHATIN' named entity 'CYTOTOXICITY' named entity 'ESTABLISHED' named entity 'CELL LINE' named entity 'CONVERSION' named entity 'ACTIVITIES' named entity 'SESQUITERPENE LACTONE' named entity 'DETERMINED BY' named entity 'AQUEOUS' named entity 'XANTHATIN' named entity 'ANTIVIRAL' named entity 'CYTOTOXIC' named entity 'XANTHIUM SPINOSUM' named entity 'ITS' named entity 'EXTRACTION' named entity 'OUR' named entity 'XANTHININ' named entity 'TIME' named entity 'IN VITRO' named entity 'LOSS OF' named entity 'CAPACITY' named entity '282' named entity 'HUMAN CELL LINES' named entity 'REVEAL' named entity 'ANTI-ANGIOGENESIS' named entity 'ITS' named entity 'CONFIRMED BY' named entity 'XANTHIUM SPINOSUM' covid:arg/b95dae179ce90376b0367517e1521a16186653a7 named entity 'determined' named entity 'time' named entity 'aqueous' named entity 'conversion' named entity 'X-ray diffraction' named entity 'natural compound' named entity 'Xanthium spinosum' named entity 'spectroscopic methods' named entity 'cell line' named entity 'human cell lines' named entity 'Xanthium spinosum' named entity 'loss' named entity 'paclitaxel' named entity 'coxsackie virus' named entity 'tumor' named entity 'angiogenesis' named entity 'solvent' named entity 'Student's t-test' named entity 'examined microscopically' named entity 'lactone' named entity 'anti-angiogenic' named entity 'HepG2' named entity 'L1210' named entity 'X-ray diffraction'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software