About: Virus purification and enrichment by hydroxyapatite chromatography on a chip

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virus purification and enrichment by hydroxyapatite chromatography on a chip
Creator	Nakamura, Shota Arai, Fumihito Kaihatsu, Kunihiro Kato, Nobuo Masuda, Taisuke Nakaya, Takaaki Niimi, Miyako
Source	Elsevier; Medline; PMC
abstract	The spread of infectious diseases has become a global health concern. In order to diagnose infectious diseases quickly and accurately, next-generation DNA sequencing techniques for genetic analysis of infectious viruses have been developed rapidly. However, it takes a very long time to pretreat clinical samples for genetic analysis using next-generation sequencers. We have therefore developed a microfluidic chromatography chip that can purify and enrich viruses in a sample using hydroxyapatite particles packed in a micro-column. We demonstrated the purification of virus from a mixture of virus and FBS protein, and enrichment of the virus using this novel microfluidic chip.
has issue date	2014-10-01(xsd:dateTime)
bibo:doi	10.1016/j.snb.2014.04.011
bibo:pmid	32288247
has license	no-cc
sha1sum (hex)	b896a30f151326e3771fa5716674fb0d3d62af2c
schema:url	https://doi.org/10.1016/j.snb.2014.04.011
resource representing a document's title	Virus purification and enrichment by hydroxyapatite chromatography on a chip
has PubMed Central identifier	PMC7111472
has PubMed identifier	32288247
schema:publication	Sens Actuators B Chem
resource representing a document's body	covid:b896a30f151326e3771fa5716674fb0d3d62af2c#body_text
is schema:about of	named entity 'HYDROXYAPATITE' named entity 'CHIP' named entity 'CHROMATOGRAPHY' named entity 'ENRICHMENT' named entity 'VIRUS' named entity 'PACKED' named entity 'PATHOGENESIS' named entity 'INFECTIOUS' named entity 'VIRUSES' named entity 'CURRENT' named entity 'GLOBAL HEALTH' named entity 'DNA SEQUENCING' named entity 'PURIFICATION' named entity 'UNDERSTAND' named entity 'COLUMN' named entity 'RAPIDLY' named entity 'GENERATION' named entity 'GENETIC ANALYSIS' named entity 'HAVE' named entity 'VIRAL INFECTIONS' named entity 'SAMPLE' named entity 'MOLECULAR MECHANISM' named entity 'DIAGNOSE' named entity 'ORDER' named entity 'TIME' named entity 'PURIFY' named entity 'USING' named entity 'PURIFICATION' named entity 'SEQUENCING TECHNIQUES' named entity 'ENRICH' named entity 'CHIP' named entity 'MICRO-' named entity 'VIRUS' named entity 'CLINICAL' named entity 'NOVEL' named entity 'DEMONSTRATED' named entity 'INFLUENZA VIRUSES' named entity 'PROTEIN' named entity 'PARTICLES' named entity 'MICROFLUIDIC' named entity 'CONCERN' named entity 'FBS' named entity 'INFECTIOUS DISEASES' named entity 'ANALYSIS' named entity 'HYDROXYAPATITE' named entity 'ENRICHMENT' named entity 'LONG' named entity 'SPREAD' named entity 'MIXTURE' named entity 'SAMPLES' named entity 'CHROMATOGRAPHY' named entity 'RESEARCH PROJECTS' named entity 'HUMANS' named entity 'pathogenesis' named entity 'viruses' named entity 'microfluidic' named entity 'global health' named entity 'next-generation DNA sequencing' named entity 'microfluidic chip' named entity 'hydroxyapatite' named entity 'hydroxyapatite' named entity 'genome' named entity 'chromatography' named entity 'virus' named entity 'hemagglutination' named entity 'RNA' named entity 'electrically charged' named entity 'plasma' named entity 'microfluidic' named entity 'microfluidic chip' named entity 'real-time RT-PCR' named entity 'chromatography' named entity 'Nagoya University' named entity 'hydroxyapatite' named entity 'Boston'

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