About: 4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids

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About: 4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids
Creator	Bereznyakova, N Turaibei, I Ukrainets, I
Source	Medline; PMC
abstract	Dialkylaminoalkylamides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids have been obtained as potential antiviral agents. The special features of the spatial structure of one example of the synthesized compounds have been studied. Results are given of the investigation of cytotoxicity and antiviral activity in relation to type 1 herpes virus and coronavirus.
has issue date	2008-05-31(xsd:dateTime)
bibo:doi	10.1007/s10593-008-0012-x
bibo:pmid	32214416
has license	no-cc
sha1sum (hex)	b6e6938e1c0fa985dfdc35a9868084b2388fb3fc
schema:url	https://doi.org/10.1007/s10593-008-0012-x
resource representing a document's title	4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids
has PubMed Central identifier	PMC7088292
has PubMed identifier	32214416
schema:publication	Chem Heterocycl Compd (N Y)
resource representing a document's body	covid:b6e6938e1c0fa985dfdc35a9868084b2388fb3fc#body_text
is schema:about of	named entity 'OXO' named entity 'HYDROXY' named entity 'EXAMPLE' named entity 'SYNTHESIZED' named entity 'FEATURES' named entity 'RESULTS' named entity 'GIVEN' named entity 'ANTIVIRAL ACTIVITY' named entity 'QUINOLONES' named entity 'AMIDES' named entity 'STRUCTURE' named entity 'POTENTIAL' named entity 'ANTIVIRAL ACTIVITY' named entity 'STRUCTURE' named entity 'SPATIAL' named entity 'OBTAINED' named entity 'ANTIVIRAL AGENTS' named entity '139' named entity 'CARBOXYLIC ACIDS' named entity 'N-R' named entity 'HERPES VIRUS' named entity 'HAVE' named entity 'RELATION' named entity 'INVESTIGATION' named entity 'SPECIAL' named entity 'CYTOTOXICITY' named entity '5B1' named entity 'SYNTHESIS' named entity 'TYPE 1' named entity 'CORONAVIRUS' named entity '2-HYDROXY' named entity 'PYRIMIDINE' named entity 'AMIDES' named entity 'ANTIVIRAL ACTIVITY' named entity 'HYDROXY' named entity 'methyl' named entity 'herpes' named entity 'Ukraine' named entity 'public health' named entity 'type 6' named entity 'aqueous solutions' named entity 'pyrimidone' named entity 'HSV-1' named entity 'nutrient media' named entity 'probability' named entity 'ether' named entity 'kidney' named entity 'chicken-pox' named entity 'neutralization reaction' named entity 'cell cultures' named entity 'electron density' named entity 'cytotoxic action' named entity 'morphology' named entity 'mechanism of action' named entity 'serum' named entity 'carboxylic acids' named entity 'amides' named entity 'epidemic spread' named entity '8 days' named entity 'antiviral' named entity 'chronic fatigue syndrome' named entity 'cultured cells' named entity 'aqueous solution' named entity 'HSV-1' named entity 'valence' named entity 'conformation' named entity 'amide' named entity 'coronary vessels' named entity 'embryo' named entity 'bovine' named entity 'carboxylic acids' named entity 'viruses' named entity 'Eagle's medium' named entity 'shingles' named entity 'hemagglutinating' named entity 'Herpesviridae' named entity 'microscope' named entity 'AIDS' named entity 'water-soluble'

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