About: Asthma in patients hospitalized with pandemic influenza A(H1N1)pdm09 virus infection

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About: Asthma in patients hospitalized with pandemic influenza A(H1N1)pdm09 virus infection–United States, 2009 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Asthma in patients hospitalized with pandemic influenza A(H1N1)pdm09 virus infection–United States, 2009
Creator	Finelli, Lyn Bramley, Anna Jain, Seema Rolfs, Robert Fry, Alicia Walker, John Arnold, Kathryn Avery, Catherine Brannan, Lesley Cocoros, Noelle Crockett, Molly Druckenmiller, Jean Geissler, Aimee Hall-Meyer, ; Hawaii, ; Jones, Tim Kirschke, David Lett, Susan Lofy, Kathrine Luke's South Hospital, Kathleen Mckenna, John Nielsen, Carrie Ragan, Patti Skarbinski, Jacek South, St, ; Sugerman, David Vernon, Valoree West, ; Wyoming, ;
Source	PMC
abstract	BACKGROUND: Asthma was the most common co-morbidity among patients hospitalized with pandemic influenza A(H1N1)pdm09 [pH1N1] infection. The objective was to compare characteristics of hospitalized pH1N1 patients with and without asthma and assess factors associated with severity among asthma patients. METHODS: Patient data were derived from two 2009 pandemic case-series of U.S. pH1N1 hospitalizations. A case was defined as a person ≥ 2 years old hospitalized with laboratory-confirmed pH1N1. Asthma status was determined through chart review. RESULTS: Among 473 cases, 29% had asthma. Persons with asthma were more likely to be 2–17 years old (39% vs. 30%, p = 0.04) and black (29% vs. 18%, p < 0.01), and have chronic obstructive pulmonary disease (13% vs. 9%, p = 0.04) but less likely to have pneumonia (37% vs. 47%, p = 0.05), need mechanical ventilation (13% vs. 23%, p = 0.02), and die (4% vs. 10%, p = 0.04) than those without asthma. Among patients with asthma, those admitted to an intensive care unit (ICU) or who died (n = 38) compared with survivors not admitted to an ICU (n = 99) were more likely to have pneumonia on admission (60% vs. 27%, p < 0.01) or acute respiratory distress syndrome (24% vs. 0%, p < 0.01) and less likely to receive influenza antiviral agents ≤ 2 days of admission (73% vs. 92%, p = 0.02). CONCLUSIONS: The majority of persons with asthma had an uncomplicated course; however, severe disease, including ICU admission and death, occurred in asthma patients who presented with pneumonia. Influenza antiviral agents should be started early in hospitalized patients with suspected influenza, including those with asthma.
has issue date	2013-01-31(xsd:dateTime)
bibo:doi	10.1186/1471-2334-13-57
bibo:pmid	23369034
has license	cc-by
sha1sum (hex)	b6b65ac8ed9668bcf77ca295b85379d31ef9996a
schema:url	https://doi.org/10.1186/1471-2334-13-57
resource representing a document's title	Asthma in patients hospitalized with pandemic influenza A(H1N1)pdm09 virus infection–United States, 2009
has PubMed Central identifier	PMC3585510
has PubMed identifier	23369034
schema:publication	BMC Infect Dis
resource representing a document's body	covid:b6b65ac8ed9668bcf77ca295b85379d31ef9996a#body_text
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