About: The prevalence of respiratory pathogens in adults with community-acquired pneumonia in an outpatient cohort

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About: The prevalence of respiratory pathogens in adults with community-acquired pneumonia in an outpatient cohort Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The prevalence of respiratory pathogens in adults with community-acquired pneumonia in an outpatient cohort
Creator	Wang, Wei Chen, Jing Xu, Jie Li, Xiaoguang Jia, Ying Lin, Fei
Source	Medline; PMC
abstract	PURPOSE: Community-acquired pneumonia is a common illness worldwide. In adults, community-acquired bacterial pneumonia has been well studied, but viral pneumonia is less well understood. We designed this study to identify respiratory pathogens, including common pneumonia-causing bacteria, viruses and atypical pneumonia pathogens, using reverse transcription-polymerase chain reaction. PATIENTS AND METHODS: We conducted a retrospective study of outpatients with community-acquired pneumonia at the Fever Clinic of Peking University Third Hospital. We collected sputum or throat swabs from patients diagnosed with community-acquired pneumonia. Multiplex real-time reverse transcription-polymerase chain reaction was performed for 20 pathogens, including 9 viruses, 3 atypical pathogens and 8 bacteria. RESULTS: There were 232 outpatients enrolled in our study, and 153 patients (65.9%) had positive test results, of which 26.7% were viruses, 19.4% were atypical pathogens and 19.8% were bacteria. Mycoplasma pneumoniae infection was detected at the highest frequency (19.0%), exceeding Streptococcus pneumoniae infection. The most commonly identified viral pathogens were IFVs (15.1%), PIVs (3.4%) and RhV (2.6%). The most commonly identified bacteria were Streptococcus pneumoniae (9.1%), Haemophilus influenza (6.5%) and Klebsiella pneumoniae (2.6%). CONCLUSION: Our study suggests that viruses were commonly detected in outpatients with CAP, and IFVs were the most common viruses, especially during flu season. Patients with viral infection were prone to viral-bacterial coinfection. Mycoplasma pneumoniae was the leading pathogen in the outpatients with CAP. Viral infection occurs in a large number of outpatients with CAP, and it should receive greater attention in clinical work.
has issue date	2019-07-30(xsd:dateTime)
bibo:doi	10.2147/idr.s213296
bibo:pmid	31440068
has license	cc-by-nc
sha1sum (hex)	b55aa037b62821a2bcf4463f30caba8c8e662e2b
schema:url	https://doi.org/10.2147/idr.s213296
resource representing a document's title	The prevalence of respiratory pathogens in adults with community-acquired pneumonia in an outpatient cohort
has PubMed Central identifier	PMC6679678
has PubMed identifier	31440068
schema:publication	Infect Drug Resist
resource representing a document's body	covid:b55aa037b62821a2bcf4463f30caba8c8e662e2b#body_text
is schema:about of	named entity 'THROAT' named entity 'IS A' named entity 'VIRAL PNEUMONIA' named entity 'BACTERIAL PNEUMONIA' named entity 'PURPOSE' named entity 'PEKING' named entity 'POLYMERASE CHAIN REACTION' named entity 'ATYPICAL' named entity 'SWABS' named entity 'HOSPITAL' named entity 'BUT' named entity 'USING' named entity 'UNDERSTOOD' named entity 'retrospective study' named entity 'pathogens' named entity 'ADULTS' named entity 'PERFORMED' named entity 'PNEUMONIA' named entity 'COMMUNITY-ACQUIRED PNEUMONIA' named entity 'RESPIRATORY PATHOGENS' named entity 'ATYPICAL PNEUMONIA' named entity 'REVERSE TRANSCRIPTION' named entity 'COLLECTED' named entity 'PATHOGENS' named entity 'COHORT' named entity 'OUTPATIENT' named entity 'PREVALENCE' named entity 'ADULTS' named entity 'METHODS' named entity 'CAUSING' named entity 'UNIVERSITY' named entity 'REAL-TIME' named entity 'COMMON' named entity 'PATIENTS' named entity 'SPUTUM' named entity 'ILLNESS' named entity 'RETROSPECTIVE STUDY' named entity 'WORLDWIDE' named entity 'RESPIRATORY PATHOGENS' named entity 'BACTERIA' named entity 'ACQUIRED' named entity 'TO IDENTIFY' named entity 'BACTERIA.' named entity 'FEVER CLINIC' named entity 'COMMUNITY-ACQUIRED PNEUMONIA' named entity 'INCLUDING' named entity 'MULTIPLEX' named entity 'DIAGNOSED' named entity 'VIRUSES' named entity 'COMMUNITY' named entity 'A COMMON' named entity 'OUTPATIENTS' named entity 'STUDY' covid:arg/b55aa037b62821a2bcf4463f30caba8c8e662e2b named entity 'community-acquired pneumonia' named entity 'sputum' named entity 'viral pneumonia' named entity 'worldwide' named entity 'pathogens' named entity 'illness' named entity 'swabs' named entity 'community-acquired pneumonia' named entity 'pathogens' named entity 'pathogens' named entity 'bacteria' named entity 'Community-acquired pneumonia' named entity 'pneumonia' named entity 'influenza A virus' named entity 'Klebsiella pneumoniae' named entity 'viral infection' named entity 'pathogens' named entity 'CAP' named entity 'hMPV' named entity 'pathogens' named entity 'CAP' named entity 'Haemophilus influenzae'

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